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Binding of the Fap2 protein of Fusobacterium nucleatum to human inhibitory receptor TIGIT protects tumors from immune cell attack.
Gur C, Ibrahim Y, Isaacson B, Yamin R, Abed J, Gamliel M, Enk J, Bar-On Y, Stanietsky-Kaynan N, Coppenhagen-Glazer S, Shussman N, Almogy G, Cuapio A, Hofer E, Mevorach D, Tabib A, Ortenberg R, Markel G, Miklić K, Jonjic S, Brennan CA, Garrett WS, Bachrach G, Mandelboim O. Gur C, et al. Among authors: hofer e. Immunity. 2015 Feb 17;42(2):344-355. doi: 10.1016/j.immuni.2015.01.010. Epub 2015 Feb 10. Immunity. 2015. PMID: 25680274 Free PMC article.
Maintenance therapy with histamine plus IL-2 induces a striking expansion of two CD56bright NK cell subpopulations in patients with acute myeloid leukemia and supports their activation.
Cuapio A, Post M, Cerny-Reiterer S, Gleixner KV, Stefanzl G, Basilio J, Herndlhofer S, Sperr WR, Brons NH, Casanova E, Zimmer J, Valent P, Hofer E. Cuapio A, et al. Among authors: hofer e. Oncotarget. 2016 Jul 19;7(29):46466-46481. doi: 10.18632/oncotarget.10191. Oncotarget. 2016. PMID: 27341131 Free PMC article. Clinical Trial.
The Transcription Factor ZNF683/HOBIT Regulates Human NK-Cell Development.
Post M, Cuapio A, Osl M, Lehmann D, Resch U, Davies DM, Bilban M, Schlechta B, Eppel W, Nathwani A, Stoiber D, Spanholtz J, Casanova E, Hofer E. Post M, et al. Among authors: hofer e. Front Immunol. 2017 May 15;8:535. doi: 10.3389/fimmu.2017.00535. eCollection 2017. Front Immunol. 2017. PMID: 28555134 Free PMC article.
Ex vivo generated natural killer cells acquire typical natural killer receptors and display a cytotoxic gene expression profile similar to peripheral blood natural killer cells.
Lehmann D, Spanholtz J, Osl M, Tordoir M, Lipnik K, Bilban M, Schlechta B, Dolstra H, Hofer E. Lehmann D, et al. Among authors: hofer e. Stem Cells Dev. 2012 Nov 1;21(16):2926-38. doi: 10.1089/scd.2011.0659. Epub 2012 Jul 17. Stem Cells Dev. 2012. PMID: 22571679 Free PMC article.
465 results