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Procedures for the GMP-Compliant Production and Quality Control of [18F]PSMA-1007: A Next Generation Radiofluorinated Tracer for the Detection of Prostate Cancer.
Cardinale J, Martin R, Remde Y, Schäfer M, Hienzsch A, Hübner S, Zerges AM, Marx H, Hesse R, Weber K, Smits R, Hoepping A, Müller M, Neels OC, Kopka K. Cardinale J, et al. Among authors: hoepping a. Pharmaceuticals (Basel). 2017 Sep 27;10(4):77. doi: 10.3390/ph10040077. Pharmaceuticals (Basel). 2017. PMID: 28953234 Free PMC article.
LC-MS Supported Studies on the in Vitro Metabolism of both Enantiomers of Flubatine and the in Vivo Metabolism of (+)-[(18)F]Flubatine-A Positron Emission Tomography Radioligand for Imaging α4β2 Nicotinic Acetylcholine Receptors.
Ludwig FA, Smits R, Fischer S, Donat CK, Hoepping A, Brust P, Steinbach J. Ludwig FA, et al. Among authors: hoepping a. Molecules. 2016 Sep 8;21(9):1200. doi: 10.3390/molecules21091200. Molecules. 2016. PMID: 27617996 Free PMC article.
Synthesis and biological evaluation of both enantiomers of [(18)F]flubatine, promising radiotracers with fast kinetics for the imaging of α4β2-nicotinic acetylcholine receptors.
Smits R, Fischer S, Hiller A, Deuther-Conrad W, Wenzel B, Patt M, Cumming P, Steinbach J, Sabri O, Brust P, Hoepping A. Smits R, et al. Among authors: hoepping a. Bioorg Med Chem. 2014 Jan 15;22(2):804-12. doi: 10.1016/j.bmc.2013.12.011. Epub 2013 Dec 12. Bioorg Med Chem. 2014. PMID: 24369841
Development of a Novel Nonpeptidic (18)F-Labeled Radiotracer for in Vivo Imaging of Oxytocin Receptors with Positron Emission Tomography.
Wenzel B, Mollitor J, Deuther-Conrad W, Dukic-Stefanovic S, Kranz M, Vraka C, Teodoro R, Günther R, Donat CK, Ludwig FA, Fischer S, Smits R, Wadsak W, Mitterhauser M, Steinbach J, Hoepping A, Brust P. Wenzel B, et al. Among authors: hoepping a. J Med Chem. 2016 Mar 10;59(5):1800-17. doi: 10.1021/acs.jmedchem.5b01080. Epub 2016 Feb 3. J Med Chem. 2016. PMID: 26796795
Enhanced copper-mediated (18)F-fluorination of aryl boronic esters provides eight radiotracers for PET applications.
Preshlock S, Calderwood S, Verhoog S, Tredwell M, Huiban M, Hienzsch A, Gruber S, Wilson TC, Taylor NJ, Cailly T, Schedler M, Collier TL, Passchier J, Smits R, Mollitor J, Hoepping A, Mueller M, Genicot C, Mercier J, Gouverneur V. Preshlock S, et al. Among authors: hoepping a. Chem Commun (Camb). 2016 Jun 28;52(54):8361-4. doi: 10.1039/c6cc03295h. Chem Commun (Camb). 2016. PMID: 27241832
Radiation dosimetry of the α4β2 nicotinic receptor ligand (+)-[18F]flubatine, comparing preclinical PET/MRI and PET/CT to first-in-human PET/CT results.
Kranz M, Sattler B, Tiepolt S, Wilke S, Deuther-Conrad W, Donat CK, Fischer S, Patt M, Schildan A, Patt J, Smits R, Hoepping A, Steinbach J, Sabri O, Brust P. Kranz M, et al. Among authors: hoepping a. EJNMMI Phys. 2016 Dec;3(1):25. doi: 10.1186/s40658-016-0160-5. Epub 2016 Oct 21. EJNMMI Phys. 2016. PMID: 27770429 Free PMC article.
Internal dose assessment of (-)-18F-flubatine, comparing animal model datasets of mice and piglets with first-in-human results.
Sattler B, Kranz M, Starke A, Wilke S, Donat CK, Deuther-Conrad W, Patt M, Schildan A, Patt J, Smits R, Hoepping A, Schoenknecht P, Steinbach J, Brust P, Sabri O. Sattler B, et al. Among authors: hoepping a. J Nucl Med. 2014 Nov;55(11):1885-92. doi: 10.2967/jnumed.114.137059. Epub 2014 Oct 6. J Nucl Med. 2014. PMID: 25286922 Free article.
Evaluation of metabolism, plasma protein binding and other biological parameters after administration of (-)-[(18)F]Flubatine in humans.
Patt M, Becker GA, Grossmann U, Habermann B, Schildan A, Wilke S, Deuther-Conrad W, Graef S, Fischer S, Smits R, Hoepping A, Wagenknecht G, Steinbach J, Gertz HJ, Hesse S, Schönknecht P, Brust P, Sabri O. Patt M, et al. Among authors: hoepping a. Nucl Med Biol. 2014 Jul;41(6):489-94. doi: 10.1016/j.nucmedbio.2014.03.018. Epub 2014 Mar 29. Nucl Med Biol. 2014. PMID: 24768146
35 results