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Page 1
DNA repair in cardiomyocytes is critical for maintaining cardiac function in mice.
de Boer M, Te Lintel Hekkert M, Chang J, van Thiel BS, Martens L, Bos MM, de Kleijnen MGJ, Ridwan Y, Octavia Y, van Deel ED, Blonden LA, Brandt RMC, Barnhoorn S, Bautista-Niño PK, Krabbendam-Peters I, Wolswinkel R, Arshi B, Ghanbari M, Kupatt C, de Windt LJ, Danser AHJ, van der Pluijm I, Remme CA, Stoll M, Pothof J, Roks AJM, Kavousi M, Essers J, van der Velden J, Hoeijmakers JHJ, Duncker DJ. de Boer M, et al. Among authors: hoeijmakers jhj. Aging Cell. 2023 Mar;22(3):e13768. doi: 10.1111/acel.13768. Epub 2023 Feb 8. Aging Cell. 2023. PMID: 36756698 Free PMC article.
Corrigendum: The use of progeroid DNA repair-deficient mice for assessing anti-aging compounds, illustrating the benefits of nicotinamide riboside.
Birkisdóttir MB, van Galen I, Brandt RMC, Barnhoorn S, van Vliet N, van Dijk C, Nagarajah B, Imholz S, van Oostrom CT, Reiling E, Gyenis Á, Mastroberardino PG, Jaarsma D, van Steeg H, Hoeijmakers JHJ, Dollé MET, Vermeij WP. Birkisdóttir MB, et al. Among authors: hoeijmakers jhj. Front Aging. 2022 Nov 23;3:1086552. doi: 10.3389/fragi.2022.1086552. eCollection 2022. Front Aging. 2022. PMID: 36506463 Free PMC article.
Purkinje-cell-specific DNA repair-deficient mice reveal that dietary restriction protects neurons by cell-intrinsic preservation of genomic health.
Birkisdóttir MB, Van't Sant LJ, Brandt RMC, Barnhoorn S, Hoeijmakers JHJ, Vermeij WP, Jaarsma D. Birkisdóttir MB, et al. Among authors: hoeijmakers jhj. Front Aging Neurosci. 2023 Jan 24;14:1095801. doi: 10.3389/fnagi.2022.1095801. eCollection 2022. Front Aging Neurosci. 2023. PMID: 36760711 Free PMC article.
Trichothiodystrophy-associated MPLKIP maintains DBR1 levels for proper lariat debranching and ectodermal differentiation.
Theil AF, Pines A, Kalayci T, Heredia-Genestar JM, Raams A, Rietveld MH, Sridharan S, Tanis SE, Mulder KW, Büyükbabani N, Karaman B, Uyguner ZO, Kayserili H, Hoeijmakers JH, Lans H, Demmers JA, Pothof J, Altunoglu U, El Ghalbzouri A, Vermeulen W. Theil AF, et al. EMBO Mol Med. 2023 Nov 8;15(11):e17973. doi: 10.15252/emmm.202317973. Epub 2023 Oct 6. EMBO Mol Med. 2023. PMID: 37800682 Free PMC article.
Hybrid Molecular and Functional Micro-CT Imaging Reveals Increased Myocardial Apoptosis Preceding Cardiac Failure in Progeroid Ercc1 Mice.
van Thiel BS, de Boer M, Ridwan Y, de Kleijnen MGJ, van Vliet N, van der Linden J, de Beer I, van Heijningen PM, Vermeij WP, Hoeijmakers JHJ, Danser AHJ, Kanaar R, Duncker DJ, van der Pluijm I, Essers J. van Thiel BS, et al. Among authors: hoeijmakers jhj. Mol Imaging Biol. 2024 Mar 18. doi: 10.1007/s11307-024-01902-4. Online ahead of print. Mol Imaging Biol. 2024. PMID: 38498063
Metabolomic analysis of dietary-restriction-induced attenuation of sarcopenia in prematurely aging DNA repair-deficient mice.
He Y, Yang W, Huang L, Mever MA, Ramautar R, Harms A, Rijksen Y, Brandt RMC, Barnhoorn S, Smit K, Jaarsma D, Lindenburg P, Hoeijmakers JHJ, Vermeij WP, Hankemeier T. He Y, et al. Among authors: hoeijmakers jhj. J Cachexia Sarcopenia Muscle. 2024 Apr 30. doi: 10.1002/jcsm.13433. Online ahead of print. J Cachexia Sarcopenia Muscle. 2024. PMID: 38689513 Free article.
Gene expression changes in cerebellum induced by dietary restriction.
Van't Sant LJ, Birkisdóttir MB, Ozinga RA, Gyenis Á, Hoeijmakers JHJ, Vermeij WP, Jaarsma D. Van't Sant LJ, et al. Among authors: hoeijmakers jhj. Front Mol Neurosci. 2023 May 24;16:1185665. doi: 10.3389/fnmol.2023.1185665. eCollection 2023. Front Mol Neurosci. 2023. PMID: 37293544 Free PMC article.
Frailty and sarcopenia within the earliest national Dutch childhood cancer survivor cohort (DCCSS-LATER): a cross-sectional study.
van Atteveld JE, de Winter DTC, Pluimakers VG, Fiocco M, Nievelstein RAJ, Hobbelink MGG, Kremer LCM, Grootenhuis MA, Maurice-Stam H, Tissing WJE, de Vries ACH, Loonen JJ, van Dulmen-den Broeder E, van der Pal HJH, Pluijm SMF, van der Heiden-van der Loo M, Versluijs AB, Louwerens M, Bresters D, van Santen HM, Hoefer I, van den Berg SAA, den Hartogh J, Hoeijmakers JHJ, Neggers SJCMM, van den Heuvel-Eibrink MM; Dutch LATER study group. van Atteveld JE, et al. Among authors: hoeijmakers jhj. Lancet Healthy Longev. 2023 Apr;4(4):e155-e165. doi: 10.1016/S2666-7568(23)00020-X. Lancet Healthy Longev. 2023. PMID: 37003274 Free article.
Time is ticking faster for long genes in aging.
Soheili-Nezhad S, Ibáñez-Solé O, Izeta A, Hoeijmakers JHJ, Stoeger T. Soheili-Nezhad S, et al. Among authors: hoeijmakers jhj. Trends Genet. 2024 Apr;40(4):299-312. doi: 10.1016/j.tig.2024.01.009. Epub 2024 Mar 21. Trends Genet. 2024. PMID: 38519330 Free article. Review.
187 results