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eIF4A1-dependent mRNAs employ purine-rich 5'UTR sequences to activate localised eIF4A1-unwinding through eIF4A1-multimerisation to facilitate translation.
Schmidt T, Dabrowska A, Waldron JA, Hodge K, Koulouras G, Gabrielsen M, Munro J, Tack DC, Harris G, McGhee E, Scott D, Carlin LM, Huang D, Le Quesne J, Zanivan S, Wilczynska A, Bushell M. Schmidt T, et al. Among authors: hodge k. Nucleic Acids Res. 2023 Feb 28;51(4):1859-1879. doi: 10.1093/nar/gkad030. Nucleic Acids Res. 2023. PMID: 36727461 Free PMC article.
Engineered immunomodulatory extracellular vesicles derived from epithelial cells acquire capacity for positive and negative T cell co-stimulation in cancer and autoimmunity.
Kugeratski FG, LeBleu VS, Dowlatshahi DP, Sugimoto H, Arian KA, Fan Y, Huang L, Wells D, Lilla S, Hodge K, Zanivan S, McAndrews KM, Kalluri R. Kugeratski FG, et al. Among authors: hodge k. bioRxiv [Preprint]. 2023 Nov 4:2023.11.02.565371. doi: 10.1101/2023.11.02.565371. bioRxiv. 2023. PMID: 37961535 Free PMC article. Preprint.
Omentum-derived matrix enables the study of metastatic ovarian cancer and stromal cell functions in a physiologically relevant environment.
Neilson LJ, Cartwright D, Risteli M, Jokinen EM, McGarry L, Sandvik T, Nikolatou K, Hodge K, Atkinson S, Vias M, Kay EJ, Brenton JD, Carlin LM, Bryant DM, Salo T, Zanivan S. Neilson LJ, et al. Among authors: hodge k. Matrix Biol Plus. 2023 Nov 22;19-20:100136. doi: 10.1016/j.mbplus.2023.100136. eCollection 2023 Dec. Matrix Biol Plus. 2023. PMID: 38223308 Free PMC article.
Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3' UTR of FAIM2.
Littleton SH, Trang KB, Volpe CM, Cook K, DeBruyne N, Maguire JA, Weidekamp MA, Hodge KM, Boehm K, Lu S, Chesi A, Bradfield JP, Pippin JA, Anderson SA, Wells AD, Pahl MC, Grant SFA. Littleton SH, et al. Among authors: hodge km. Cell Genom. 2024 May 8;4(5):100556. doi: 10.1016/j.xgen.2024.100556. Epub 2024 May 1. Cell Genom. 2024. PMID: 38697123
The association between neighborhood deprivation and DNA methylation in an autopsy cohort.
Pett L, Li Z, Abrishamcar S, Hodge K, Everson T, Christensen G, Gearing M, Kobor MS, Konwar C, MacIsaac JL, Dever K, Wingo AP, Levey A, Lah JJ, Wingo TS, Hüls A. Pett L, et al. Among authors: hodge k. Aging (Albany NY). 2024 Apr 24;16(8):6694-6716. doi: 10.18632/aging.205764. Epub 2024 Apr 24. Aging (Albany NY). 2024. PMID: 38663907 Free PMC article.
Epigenetic associations in HPA axis genes related to bronchopulmonary dysplasia and antenatal steroids.
Hodge KM, Zhabotynsky V, Burt AA, Carter BS, Fry RC, Helderman J, Hofheimer JA, McGowan EC, Neal CR, Pastyrnak SL, Smith LM, DellaGrotta SA, Dansereau LM, Lester BM, Marsit CJ, O'Shea TM, Everson TM; program collaborators for Environmental influences on Child Health Outcomes. Hodge KM, et al. Pediatr Res. 2024 Mar 13. doi: 10.1038/s41390-024-03116-4. Online ahead of print. Pediatr Res. 2024. PMID: 38480856
Tominersen in Adults with Manifest Huntington's Disease.
McColgan P, Thobhani A, Boak L, Schobel SA, Nicotra A, Palermo G, Trundell D, Zhou J, Schlegel V, Sanwald Ducray P, Hawellek DJ, Dorn J, Simillion C, Lindemann M, Wheelock V, Durr A, Anderson KE, Long JD, Wild EJ, Landwehrmeyer GB, Leavitt BR, Tabrizi SJ, Doody R; GENERATION HD1 Investigators. McColgan P, et al. N Engl J Med. 2023 Dec 7;389(23):2203-2205. doi: 10.1056/NEJMc2300400. N Engl J Med. 2023. PMID: 38055260 No abstract available.
Evaluation of a quality improvement intervention to reduce anastomotic leak following right colectomy (EAGLE): pragmatic, batched stepped-wedge, cluster-randomized trial in 64 countries.
ESCP EAGLE Safe Anastomosis Collaborative and NIHR Global Health Research Unit in Surgery. ESCP EAGLE Safe Anastomosis Collaborative and NIHR Global Health Research Unit in Surgery. Br J Surg. 2024 Jan 3;111(1):znad370. doi: 10.1093/bjs/znad370. Br J Surg. 2024. PMID: 38029386 Free PMC article. Clinical Trial.
221 results