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Clofoctol inhibits SARS-CoV-2 replication and reduces lung pathology in mice.
Belouzard S, Machelart A, Sencio V, Vausselin T, Hoffmann E, Deboosere N, Rouillé Y, Desmarets L, Séron K, Danneels A, Robil C, Belloy L, Moreau C, Piveteau C, Biela A, Vandeputte A, Heumel S, Deruyter L, Dumont J, Leroux F, Engelmann I, Alidjinou EK, Hober D, Brodin P, Beghyn T, Trottein F, Deprez B, Dubuisson J. Belouzard S, et al. Among authors: hober d. PLoS Pathog. 2022 May 19;18(5):e1010498. doi: 10.1371/journal.ppat.1010498. eCollection 2022 May. PLoS Pathog. 2022. PMID: 35587469 Free PMC article.
Coxsackievirus B4 can infect human pancreas ductal cells and persist in ductal-like cell cultures which results in inhibition of Pdx1 expression and disturbed formation of islet-like cell aggregates.
Sane F, Caloone D, Gmyr V, Engelmann I, Belaich S, Kerr-Conte J, Pattou F, Desailloud R, Hober D. Sane F, et al. Among authors: hober d. Cell Mol Life Sci. 2013 Nov;70(21):4169-80. doi: 10.1007/s00018-013-1383-4. Epub 2013 Jun 18. Cell Mol Life Sci. 2013. PMID: 23775130
280 results