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Macrophage migration inhibitory factor (MIF) modulates trophic signaling through interaction with serine protease HTRA1.
Fex Svenningsen Å, Löring S, Sørensen AL, Huynh HUB, Hjæresen S, Martin N, Moeller JB, Elkjær ML, Holmskov U, Illes Z, Andersson M, Nielsen SB, Benedikz E. Fex Svenningsen Å, et al. Among authors: hjaeresen s. Cell Mol Life Sci. 2017 Dec;74(24):4561-4572. doi: 10.1007/s00018-017-2592-z. Epub 2017 Jul 19. Cell Mol Life Sci. 2017. PMID: 28726057 Free PMC article.
The levels of the serine protease HTRA1 in cerebrospinal fluid correlate with progression and disability in multiple sclerosis.
Hjæresen S, Sejbaek T, Axelsson M, Vinsløv-Jensen H, Mortensen SK, Pihl-Jensen G, Novakova L, Christensen JDR, Pedersen CB, Halle B, Poulsen FR, Lautrup Frederiksen J, Zhang M, Benedikz E, Lycke J, Illes Z, Fex Svenningsen Å. Hjæresen S, et al. J Neurol. 2021 Sep;268(9):3316-3324. doi: 10.1007/s00415-021-10489-7. Epub 2021 Mar 4. J Neurol. 2021. PMID: 33661357
MIF in the cerebrospinal fluid is decreased during relapsing-remitting while increased in secondary progressive multiple sclerosis.
Hjæresen S, Sejbaek T, Axelsson M, Mortensen SK, Vinsløv-Jensen H, Pihl-Jensen G, Novakova L, Pedersen CB, Halle B, Poulsen FR, Zhang M, Benedikz E, Frederiksen JL, Lycke J, Illes Z, Fex-Svenningsen Å. Hjæresen S, et al. J Neurol Sci. 2022 Aug 15;439:120320. doi: 10.1016/j.jns.2022.120320. Epub 2022 Jun 13. J Neurol Sci. 2022. PMID: 35717879
Sortilin Modulates Schwann Cell Signaling and Remak Bundle Regeneration Following Nerve Injury.
Ulrichsen M, Gonçalves NP, Mohseni S, Hjæresen S, Lisle TL, Molgaard S, Madsen NK, Andersen OM, Svenningsen ÅF, Glerup S, Nykjær A, Vægter CB. Ulrichsen M, et al. Among authors: hjaeresen s. Front Cell Neurosci. 2022 May 11;16:856734. doi: 10.3389/fncel.2022.856734. eCollection 2022. Front Cell Neurosci. 2022. PMID: 35634462 Free PMC article.
High temperature requirement A1 and macrophage migration inhibitory factor in the cerebrospinal fluid; a potential marker of conversion from relapsing-remitting to secondary progressive multiple sclerosis.
Hjæresen S, Benedikz E, Sejbaek T, Axelsson M, Novakova L, Zhang M, Lycke J, Illes Z, Fex-Svenningsen Å. Hjæresen S, et al. J Neurol Sci. 2024 Feb 15;457:122888. doi: 10.1016/j.jns.2024.122888. Epub 2024 Jan 14. J Neurol Sci. 2024. PMID: 38278096 Free article.