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Toll-like receptor dual-acting agonists are potent inducers of PBMC-produced cytokines that inhibit hepatitis B virus production in primary human hepatocytes.
Janovec V, Hodek J, Clarova K, Hofman T, Dostalik P, Fronek J, Chlupac J, Chaperot L, Durand S, Baumert TF, Pichova I, Lubyova B, Hirsch I, Weber J. Janovec V, et al. Among authors: hirsch i. Sci Rep. 2020 Jul 29;10(1):12767. doi: 10.1038/s41598-020-69614-7. Sci Rep. 2020. PMID: 32728070 Free PMC article.
Dual Role of the Tyrosine Kinase Syk in Regulation of Toll-Like Receptor Signaling in Plasmacytoid Dendritic Cells.
Aouar B, Kovarova D, Letard S, Font-Haro A, Florentin J, Weber J, Durantel D, Chaperot L, Plumas J, Trejbalova K, Hejnar J, Nunès JA, Olive D, Dubreuil P, Hirsch I, Stranska R. Aouar B, et al. Among authors: hirsch i. PLoS One. 2016 Jun 3;11(6):e0156063. doi: 10.1371/journal.pone.0156063. eCollection 2016. PLoS One. 2016. PMID: 27258042 Free PMC article.
The MEK1/2-ERK Pathway Inhibits Type I IFN Production in Plasmacytoid Dendritic Cells.
Janovec V, Aouar B, Font-Haro A, Hofman T, Trejbalova K, Weber J, Chaperot L, Plumas J, Olive D, Dubreuil P, Nunès JA, Stranska R, Hirsch I. Janovec V, et al. Among authors: hirsch i. Front Immunol. 2018 Feb 26;9:364. doi: 10.3389/fimmu.2018.00364. eCollection 2018. Front Immunol. 2018. PMID: 29535732 Free PMC article.
Hepatitis B Virus Evasion From Cyclic Guanosine Monophosphate-Adenosine Monophosphate Synthase Sensing in Human Hepatocytes.
Verrier ER, Yim SA, Heydmann L, El Saghire H, Bach C, Turon-Lagot V, Mailly L, Durand SC, Lucifora J, Durantel D, Pessaux P, Manel N, Hirsch I, Zeisel MB, Pochet N, Schuster C, Baumert TF. Verrier ER, et al. Among authors: hirsch i. Hepatology. 2018 Nov;68(5):1695-1709. doi: 10.1002/hep.30054. Epub 2018 Jul 10. Hepatology. 2018. PMID: 29679386 Free PMC article.
787 results