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Identification of inhibitors targeting the energy-coupling factor (ECF) transporters.
Diamanti E, Souza PCT, Setyawati I, Bousis S, Monjas L, Swier LJYM, Shams A, Tsarenko A, Stanek WK, Jäger M, Marrink SJ, Slotboom DJ, Hirsch AKH. Diamanti E, et al. Among authors: hirsch akh. Commun Biol. 2023 Nov 20;6(1):1182. doi: 10.1038/s42003-023-05555-x. Commun Biol. 2023. PMID: 37985798 Free PMC article.
DXS as a target for structure-based drug design.
Gierse RM, Redeem E, Diamanti E, Wrenger C, Groves MR, Hirsch AK. Gierse RM, et al. Future Med Chem. 2017 Jul;9(11):1277-1294. doi: 10.4155/fmc-2016-0239. Epub 2017 Jun 21. Future Med Chem. 2017. PMID: 28636418 Review.
Insight into the complete substrate-binding pocket of ThiT by chemical and genetic mutations.
Swier LJYM, Monjas L, Reeßing F, Oudshoorn RC, Aisyah, Primke T, Bakker MM, van Olst E, Ritschel T, Faustino I, Marrink SJ, Hirsch AKH, Slotboom DJ. Swier LJYM, et al. Among authors: hirsch akh. Medchemcomm. 2017 Mar 31;8(5):1121-1130. doi: 10.1039/c7md00079k. eCollection 2017 May 1. Medchemcomm. 2017. PMID: 30108823 Free PMC article.
Assessment of the rules related to gaining activity against Gram-negative bacteria.
Ropponen HK, Diamanti E, Siemens A, Illarionov B, Haupenthal J, Fischer M, Rottmann M, Witschel M, Hirsch AKH. Ropponen HK, et al. Among authors: hirsch akh. RSC Med Chem. 2021 Mar 3;12(4):593-601. doi: 10.1039/d0md00409j. eCollection 2021 Apr 28. RSC Med Chem. 2021. PMID: 34046630 Free PMC article.
147 results