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Blood-brain barrier penetration of non-replicating SARS-CoV-2 and S1 variants of concern induce neuroinflammation which is accentuated in a mouse model of Alzheimer's disease.
Erickson MA, Logsdon AF, Rhea EM, Hansen KM, Holden SJ, Banks WA, Smith JL, German C, Farr SA, Morley JE, Weaver RR, Hirsch AJ, Kovac A, Kontsekova E, Baumann KK, Omer MA, Raber J. Erickson MA, et al. Among authors: hirsch aj. Brain Behav Immun. 2023 Mar;109:251-268. doi: 10.1016/j.bbi.2023.01.010. Epub 2023 Jan 20. Brain Behav Immun. 2023. PMID: 36682515 Free PMC article.
Flaviviruses are sensitive to inhibition of thymidine synthesis pathways.
Fischer MA, Smith JL, Shum D, Stein DA, Parkins C, Bhinder B, Radu C, Hirsch AJ, Djaballah H, Nelson JA, Früh K. Fischer MA, et al. Among authors: hirsch aj. J Virol. 2013 Sep;87(17):9411-9. doi: 10.1128/JVI.00101-13. Epub 2013 Jul 3. J Virol. 2013. PMID: 23824813 Free PMC article.
Characterization and structure-activity relationship analysis of a class of antiviral compounds that directly bind dengue virus capsid protein and are incorporated into virions.
Smith JL, Sheridan K, Parkins CJ, Frueh L, Jemison AL, Strode K, Dow G, Nilsen A, Hirsch AJ. Smith JL, et al. Among authors: hirsch aj. Antiviral Res. 2018 Jul;155:12-19. doi: 10.1016/j.antiviral.2018.04.019. Epub 2018 Apr 27. Antiviral Res. 2018. PMID: 29709563 Free PMC article.
38 results