Hirotsu Y - Search Results

1

Consolidated BRCA1/2 Variant Interpretation by MH BRCA Correlates with Predicted PARP Inhibitor Efficacy Association by MH Guide.

Hirotsu Y, Schmidt-Edelkraut U, Nakagomi H, Sakamoto I, Hartenfeller M, Narang R, Soldatos TG, Kaduthanam S, Wang X, Hettich S, Brock S, Jackson DB, Omata M. Hirotsu Y, et al. Int J Mol Sci. 2020 May 29;21(11):3895. doi: 10.3390/ijms21113895. Int J Mol Sci. 2020. PMID: 32486089 Free PMC article.

2

HCV NS5A resistance-associated variants in a group of real-world Japanese patients chronically infected with HCV genotype 1b.

Hirotsu Y, Kanda T, Matsumura H, Moriyama M, Yokosuka O, Omata M. Hirotsu Y, et al. Hepatol Int. 2015 Jul;9(3):424-30. doi: 10.1007/s12072-015-9624-2. Epub 2015 Mar 20. Hepatol Int. 2015. PMID: 25791176

3

Detection of BRCA1 and BRCA2 germline mutations in Japanese population using next-generation sequencing.

Hirotsu Y, Nakagomi H, Sakamoto I, Amemiya K, Mochizuki H, Omata M. Hirotsu Y, et al. Mol Genet Genomic Med. 2015 Mar;3(2):121-9. doi: 10.1002/mgg3.120. Epub 2014 Dec 4. Mol Genet Genomic Med. 2015. PMID: 25802882 Free PMC article.

4

Willingness of Japanese patients with breast cancer to have genetic testing of BRCA without burden of expenses.

Nakagomi H, Sakamoto I, Hirotsu Y, Amemiya K, Mochizuki H, Inoue M, Nakagomi S, Kubota T, Omata M. Nakagomi H, et al. Among authors: hirotsu y. Breast Cancer. 2016 Jul;23(4):649-53. doi: 10.1007/s12282-015-0618-7. Epub 2015 May 30. Breast Cancer. 2016. PMID: 26025266

5

Analysis of PALB2 mutations in 155 Japanese patients with breast and/or ovarian cancer.

Nakagomi H, Sakamoto I, Hirotsu Y, Amemiya K, Mochiduki H, Omata M. Nakagomi H, et al. Among authors: hirotsu y. Int J Clin Oncol. 2016 Apr;21(2):270-275. doi: 10.1007/s10147-015-0906-4. Epub 2015 Sep 28. Int J Clin Oncol. 2016. PMID: 26411315

RESULTS: BRCA1/2 analysis was performed on 155 patients, for whom the results were reported previously (Hirotsu Y et al. Mol Genet Genomic Med, doi:10.1002/mgg3.157, 2015). Eleven patients were identified to have deleterious BRCA mutations (Hirotsu Y e …

RESULTS: BRCA1/2 analysis was performed on 155 patients, for whom the results were reported previously (Hirotsu Y et al. Mol G …

6

Multigene panel analysis identified germline mutations of DNA repair genes in breast and ovarian cancer.

Hirotsu Y, Nakagomi H, Sakamoto I, Amemiya K, Oyama T, Mochizuki H, Omata M. Hirotsu Y, et al. Mol Genet Genomic Med. 2015 Sep;3(5):459-66. doi: 10.1002/mgg3.157. Epub 2015 May 12. Mol Genet Genomic Med. 2015. PMID: 26436112 Free PMC article.

7

BRCA1 and BRCA2 mutations in Japanese patients with ovarian, fallopian tube, and primary peritoneal cancer.

Sakamoto I, Hirotsu Y, Nakagomi H, Ouchi H, Ikegami A, Teramoto K, Amemiya K, Mochizuki H, Omata M. Sakamoto I, et al. Among authors: hirotsu y. Cancer. 2016 Jan 1;122(1):84-90. doi: 10.1002/cncr.29707. Epub 2015 Oct 6. Cancer. 2016. PMID: 26439132 Free article.

8

Targeted and exome sequencing identified somatic mutations in hepatocellular carcinoma.

Hirotsu Y, Zheng TH, Amemiya K, Mochizuki H, Guleng B, Omata M. Hirotsu Y, et al. Hepatol Res. 2016 Oct;46(11):1145-1151. doi: 10.1111/hepr.12663. Epub 2016 Mar 15. Hepatol Res. 2016. PMID: 26850916

9

Analysis of tumor-derived DNA in plasma and bone marrow fluid in lung cancer patients.

Goto T, Hirotsu Y, Oyama T, Amemiya K, Omata M. Goto T, et al. Among authors: hirotsu y. Med Oncol. 2016 Mar;33(3):29. doi: 10.1007/s12032-016-0744-x. Epub 2016 Feb 20. Med Oncol. 2016. PMID: 26897174

10

A study of tumor heterogeneity in a case with breast cancer.

Nakada H, Nakagomi H, Hirotsu Y, Amemiya K, Mochizuki H, Inoue M, Oyama T, Omata M. Nakada H, et al. Among authors: hirotsu y. Breast Cancer. 2017 May;24(3):483-489. doi: 10.1007/s12282-016-0733-0. Epub 2016 Sep 29. Breast Cancer. 2017. PMID: 27687626

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