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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 1
2003 2
2004 2
2005 2
2007 6
2008 4
2009 3
2010 8
2011 9
2012 15
2013 19
2014 20
2015 17
2016 11
2017 19
2018 14
2019 11
2020 14
2021 7
2022 6
2023 7
2024 2

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172 results

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Page 1
Helix-based screening with structure prediction using artificial intelligence has potential for the rapid development of peptide inhibitors targeting class I viral fusion.
Suzuki S, Kuroda M, Aoki K, Kawaji K, Hiramatsu Y, Sasano M, Nishiyama A, Murayama K, Kodama EN, Oishi S, Hayashi H. Suzuki S, et al. Among authors: hayashi h. RSC Chem Biol. 2023 Nov 7;5(2):131-140. doi: 10.1039/d3cb00166k. eCollection 2024 Feb 7. RSC Chem Biol. 2023. PMID: 38333196 Free PMC article.
GRL-142 binds to and impairs HIV-1 integrase nuclear localization signal and potently suppresses highly INSTI-resistant HIV-1 variants.
Aoki M, Aoki-Ogata H, Bulut H, Hayashi H, Takamune N, Kishimoto N, Tanaka H, Higashi-Kuwata N, Hattori SI, Das D, Venkateswara Rao K, Iwama K, Davis DA, Hasegawa K, Murayama K, Yarchoan R, Ghosh AK, Pau AK, Machida S, Misumi S, Mitsuya H. Aoki M, et al. Among authors: hayashi h. Sci Adv. 2023 Jul 14;9(28):eadg2955. doi: 10.1126/sciadv.adg2955. Epub 2023 Jul 12. Sci Adv. 2023. PMID: 37436982 Free PMC article.
Cardiac Rehabilitation for Patients With Stable Ischemic Heart Disease Without Revascularization　- Rationale and Design of a Single-Arm Pilot Study.
Seki T, Murata M, Takabayashi K, Yanagisawa T, Ogihara M, Kurimoto R, Kida K, Tamita K, Song X, Ozasa N, Taniguchi R, Nishitani-Yokoyama M, Koba S, Murai R, Furukawa Y, Hamasaki M, Kondo H, Hayashi H, Ootakara-Katsume A, Tateishi K, Matoba S, Adachi H, Shiraishi H; START Investigators. Seki T, et al. Among authors: hayashi h. Circ Rep. 2023 Feb 25;5(3):90-94. doi: 10.1253/circrep.CR-22-0131. eCollection 2023 Mar 10. Circ Rep. 2023. PMID: 36909138 Free PMC article.
Identification of SARS-CoV-2 Mpro inhibitors containing P1' 4-fluorobenzothiazole moiety highly active against SARS-CoV-2.
Higashi-Kuwata N, Tsuji K, Hayashi H, Bulut H, Kiso M, Imai M, Ogata-Aoki H, Ishii T, Kobayakawa T, Nakano K, Takamune N, Kishimoto N, Hattori SI, Das D, Uemura Y, Shimizu Y, Aoki M, Hasegawa K, Suzuki S, Nishiyama A, Saruwatari J, Shimizu Y, Sukenaga Y, Takamatsu Y, Tsuchiya K, Maeda K, Yoshimura K, Iida S, Ozono S, Suzuki T, Okamura T, Misumi S, Kawaoka Y, Tamamura H, Mitsuya H. Higashi-Kuwata N, et al. Among authors: hayashi h. Nat Commun. 2023 Feb 25;14(1):1076. doi: 10.1038/s41467-023-36729-0. Nat Commun. 2023. PMID: 36841831 Free PMC article.
Potent and biostable inhibitors of the main protease of SARS-CoV-2.
Tsuji K, Ishii T, Kobayakawa T, Higashi-Kuwata N, Azuma C, Nakayama M, Onishi T, Nakano H, Wada N, Hori M, Shinohara K, Miura Y, Kawada T, Hayashi H, Hattori SI, Bulut H, Das D, Takamune N, Kishimoto N, Saruwatari J, Okamura T, Nakano K, Misumi S, Mitsuya H, Tamamura H. Tsuji K, et al. Among authors: hayashi h. iScience. 2022 Nov 18;25(11):105365. doi: 10.1016/j.isci.2022.105365. Epub 2022 Nov 1. iScience. 2022. PMID: 36338434 Free PMC article.
Serine hydroxymethyltransferase as a potential target of antibacterial agents acting synergistically with one-carbon metabolism-related inhibitors.
Makino Y, Oe C, Iwama K, Suzuki S, Nishiyama A, Hasegawa K, Okuda H, Hirata K, Ueno M, Kawaji K, Sasano M, Usui E, Hosaka T, Yabuki Y, Shirouzu M, Katsumi M, Murayama K, Hayashi H, Kodama EN. Makino Y, et al. Among authors: hayashi h. Commun Biol. 2022 Jun 23;5(1):619. doi: 10.1038/s42003-022-03555-x. Commun Biol. 2022. PMID: 35739195 Free PMC article.
172 results