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Oral edaravone demonstrated a favorable safety profile in patients with amyotrophic lateral sclerosis after 48 weeks of treatment.
Genge A, Pattee GL, Sobue G, Aoki M, Yoshino H, Couratier P, Lunetta C, Petri S, Selness D, Bidani S, Hirai M, Sakata T, Salah A, Apple S, Wamil A, Kalin A, Jackson CE. Genge A, et al. Among authors: hirai m. Muscle Nerve. 2023 Feb;67(2):124-129. doi: 10.1002/mus.27768. Epub 2022 Dec 28. Muscle Nerve. 2023. PMID: 36504406 Free PMC article. Clinical Trial.
Pharmacokinetics of Edaravone Oral Suspension in Patients With Amyotrophic Lateral Sclerosis.
Shimizu H, Nishimura Y, Shiide Y, Akimoto M, Yashiro M, Ueda M, Hirai M, Yoshino H, Mizutani T, Kanai K, Kano O, Kimura H, Sekino H, Ito K. Shimizu H, et al. Among authors: hirai m. Clin Ther. 2023 Dec;45(12):1251-1258. doi: 10.1016/j.clinthera.2023.09.025. Epub 2023 Nov 11. Clin Ther. 2023. PMID: 37953075 Free article. Clinical Trial.
An assessment of treatment guidelines, clinical practices, demographics, and progression of disease among patients with amyotrophic lateral sclerosis in Japan, the United States, and Europe.
Takei K, Tsuda K, Takahashi F, Hirai M, Palumbo J. Takei K, et al. Among authors: hirai m. Amyotroph Lateral Scler Frontotemporal Degener. 2017 Oct;18(sup1):88-97. doi: 10.1080/21678421.2017.1361445. Amyotroph Lateral Scler Frontotemporal Degener. 2017. PMID: 28872912 Review.
Association of a Transitional Heart Failure Management Program With Readmission and End-of-Life Care in Rural Japan.
Kinugasa Y, Nakamura K, Hirai M, Manba M, Ishiga N, Sota T, Nakayama N, Ohta T, Kato M, Adachi T, Fukuki M, Hirota Y, Mizuta E, Mura E, Nozaka Y, Omodani H, Tanaka H, Tanaka Y, Watanabe I, Mikami M, Yamamoto K. Kinugasa Y, et al. Among authors: hirai m. Circ Rep. 2024 Apr 20;6(5):168-177. doi: 10.1253/circrep.CR-24-0030. eCollection 2024 May 10. Circ Rep. 2024. PMID: 38736846 Free PMC article.
A longer-chain acylated derivative of Dictyostelium differentiation-inducing factor-1 enhances the antimalarial activity against Plasmodium parasites.
Yoshida N, Kikuchi H, Hirai M, Balikagala B, Anywar DA, Taka H, Kaga N, Miura Y, Fukuda N, Odongo-Aginya EI, Kubohara Y, Mita T. Yoshida N, et al. Among authors: hirai m. Biochem Pharmacol. 2024 Apr 30;225:116243. doi: 10.1016/j.bcp.2024.116243. Online ahead of print. Biochem Pharmacol. 2024. PMID: 38697310
1,413 results