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The inflammatory microenvironment of the lung at the time of infection governs innate control of SARS-CoV-2 replication.
Baker PJ, Bohrer AC, Castro E, Amaral EP, Snow-Smith M, Torres-Juárez F, Gould ST, Queiroz ATL, Fukutani ER, Jordan CM, Khillan JS, Cho K, Barber DL, Andrade BB, Johnson RF, Hilligan KL, Mayer-Barber KD. Baker PJ, et al. Among authors: hilligan kl. bioRxiv [Preprint]. 2024 Mar 27:2024.03.27.586885. doi: 10.1101/2024.03.27.586885. bioRxiv. 2024. PMID: 38585846 Free PMC article. Preprint.
Bacterial-induced or passively administered interferon gamma conditions the lung for early control of SARS-CoV-2.
Hilligan KL, Namasivayam S, Clancy CS, Baker PJ, Old SI, Peluf V, Amaral EP, Oland SD, O'Mard D, Laux J, Cohen M, Garza NL, Lafont BAP, Johnson RF, Feng CG, Jankovic D, Lamiable O, Mayer-Barber KD, Sher A. Hilligan KL, et al. Nat Commun. 2023 Dec 12;14(1):8229. doi: 10.1038/s41467-023-43447-0. Nat Commun. 2023. PMID: 38086794 Free PMC article.
BACH1 promotes tissue necrosis and Mycobacterium tuberculosis susceptibility.
Amaral EP, Namasivayam S, Queiroz ATL, Fukutani E, Hilligan KL, Aberman K, Fisher L, Bomfim CCB, Kauffman K, Buchanan J, Santuo L, Gazzinelli-Guimaraes PH, Costa DL, Teixeira MA, Barreto-Duarte B, Rocha CG, Santana MF, Cordeiro-Santos M, Barber DL, Wilkinson RJ, Kramnik I, Igarashi K, Scriba T, Mayer-Barber KD, Andrade BB, Sher A. Amaral EP, et al. Among authors: hilligan kl. Nat Microbiol. 2024 Jan;9(1):120-135. doi: 10.1038/s41564-023-01523-7. Epub 2023 Dec 8. Nat Microbiol. 2024. PMID: 38066332 Free PMC article.
Co-infection of mice with SARS-CoV-2 and Mycobacterium tuberculosis limits early viral replication but does not affect mycobacterial loads.
Baker PJ, Amaral EP, Castro E, Bohrer AC, Torres-Juárez F, Jordan CM, Nelson CE, Barber DL, Johnson RF, Hilligan KL, Mayer-Barber KD. Baker PJ, et al. Among authors: hilligan kl. Front Immunol. 2023 Sep 1;14:1240419. doi: 10.3389/fimmu.2023.1240419. eCollection 2023. Front Immunol. 2023. PMID: 37720210 Free PMC article.
Endogenous and Therapeutic 25-Hydroxycholesterols May Worsen Early SARS-CoV-2 Pathogenesis in Mice.
Fessler MB, Madenspacher JH, Baker PJ, Hilligan KL, Bohrer AC, Castro E, Meacham J, Chen SH, Johnson RF, McDonald JG, Martin NP, Tucker CJ, Mahapatra D, Cesta M, Mayer-Barber KD. Fessler MB, et al. Among authors: hilligan kl. Am J Respir Cell Mol Biol. 2023 Dec;69(6):638-648. doi: 10.1165/rcmb.2023-0007OC. Am J Respir Cell Mol Biol. 2023. PMID: 37578898 Free PMC article.
Exposure to lung-migrating helminth protects against murine SARS-CoV-2 infection through macrophage-dependent T cell activation.
Oyesola OO, Hilligan KL, Namasivayam S, Howard N, Clancy CS, Zhao M, Oland SD, Kiwanuka KN, Garza NL, Lafont BAP, Johnson RF, Mayer-Barber KD, Sher A, Loke P. Oyesola OO, et al. Among authors: hilligan kl. Sci Immunol. 2023 Aug 18;8(86):eadf8161. doi: 10.1126/sciimmunol.adf8161. Epub 2023 Aug 11. Sci Immunol. 2023. PMID: 37566678
Incorporation of SARS-CoV-2 spike NTD to RBD protein vaccine improves immunity against viral variants.
Montgomerie I, Bird TW, Palmer OR, Mason NC, Pankhurst TE, Lawley B, Hernández LC, Harfoot R, Authier-Hall A, Anderson DE, Hilligan KL, Buick KH, Mbenza NM, Mittelstädt G, Maxwell S, Sinha S, Kuang J, Subbarao K, Parker EJ, Sher A, Hermans IF, Ussher JE, Quiñones-Mateu ME, Comoletti D, Connor LM; VAANZ Group. Montgomerie I, et al. Among authors: hilligan kl. iScience. 2023 Apr 21;26(4):106256. doi: 10.1016/j.isci.2023.106256. Epub 2023 Feb 20. iScience. 2023. PMID: 36845030 Free PMC article.
Evaluation of endogenous and therapeutic 25-hydroxycholesterols in murine models of pulmonary SARS-CoV-2 infection.
Fessler MB, Madenspacher J, Baker PJ, Hilligan KL, Castro E, Meacham J, Chen SH, Johnson RF, Martin NP, Tucker CJ, Mahapatra D, Cesta M, Mayer-Barber KD. Fessler MB, et al. Among authors: hilligan kl. bioRxiv [Preprint]. 2022 Sep 13:2022.09.12.507671. doi: 10.1101/2022.09.12.507671. bioRxiv. 2022. PMID: 36263064 Free PMC article. Updated. Preprint.
23 results