Hill KA - Search Results

1

Relatively high rates of G:C → A:T transitions at CpG sites were observed in certain epithelial tissues including pancreas and submaxillary gland of adult big blue® mice.

Prtenjaca A, Tarnowski HE, Marr AM, Heney MA, Creamer L, Sathiamoorthy S, Hill KA. Prtenjaca A, et al. Among authors: hill ka. Environ Mol Mutagen. 2014 Jan;55(1):51-63. doi: 10.1002/em.21816. Epub 2013 Sep 17. Environ Mol Mutagen. 2014. PMID: 24105921

2

A novel germline mutation in Big Blue mice.

Crabbe RA, Prtenjaca A, Tarnowski HE, Hill KA. Crabbe RA, et al. Among authors: hill ka. Environ Mol Mutagen. 2009 Mar;50(2):114-20. doi: 10.1002/em.20442. Environ Mol Mutagen. 2009. PMID: 19107908

The frequency of spontaneous doublets (mutants with two nontandem mutations) was elevated 2.7-fold over that previously reported (Hill KA et al., [2004b]: Mutat Res 554:223-240) for normal tissues (6.3 x 10(-7) herein vs. 2.36 x 10(-7)). ...

The frequency of spontaneous doublets (mutants with two nontandem mutations) was elevated 2.7-fold over that previously reported (Hill …

3

A novel Escherichia coli-derived mutation detected with the Big Blue cII mutant selectable assay.

Ward TL, Prtenjaca A, Hill KA. Ward TL, et al. Among authors: hill ka. Environ Mol Mutagen. 2010 May;51(4):344-8. doi: 10.1002/em.20549. Environ Mol Mutagen. 2010. PMID: 20120017

4

Mutation frequency is not elevated in the cerebellum of harlequin/Big Blue(®) mice but Class II deletions occur preferentially in young harlequin cerebellum.

Prtenjaca A, Hill KA. Prtenjaca A, et al. Among authors: hill ka. Mutat Res. 2011 Feb 10;707(1-2):53-60. doi: 10.1016/j.mrfmmm.2010.12.012. Epub 2010 Dec 30. Mutat Res. 2011. PMID: 21195094

5

Spontaneous mutation frequency is elevated in skin of harlequin (hq)/Big Blue mice.

Van Osch FS, Piliguian M, Hill KA. Van Osch FS, et al. Among authors: hill ka. Mutagenesis. 2010 May;25(3):235-42. doi: 10.1093/mutage/gep069. Epub 2010 Jan 20. Mutagenesis. 2010. PMID: 20089602

6

Spontaneous mutation in Big Blue mice from fetus to old age: tissue-specific time courses of mutation frequency but similar mutation types.

Hill KA, Buettner VL, Halangoda A, Kunishige M, Moore SR, Longmate J, Scaringe WA, Sommer SS. Hill KA, et al. Environ Mol Mutagen. 2004;43(2):110-20. doi: 10.1002/em.20004. Environ Mol Mutagen. 2004. PMID: 14991751

The spectrum of mutation types was unaltered with age, tissue type and gender, although, as previously reported, tandem GG-->TT mutations are tissue specific and show significant increases with age and certain hotspots (Buettner VL et al. [1999]: Environ Mol Mutagen 33:320-324 …

The spectrum of mutation types was unaltered with age, tissue type and gender, although, as previously reported, tandem GG-->TT mutations …

7

Spontaneous microdeletions and microinsertions in a transgenic mouse mutation detection system: analysis of age, tissue, and sequence specificity.

Halangoda A, Still JG, Hill KA, Sommer SS. Halangoda A, et al. Among authors: hill ka. Environ Mol Mutagen. 2001;37(4):311-23. doi: 10.1002/em.1038. Environ Mol Mutagen. 2001. PMID: 11424181

8

Tissue-specific time courses of spontaneous mutation frequency and deviations in mutation pattern are observed in middle to late adulthood in Big Blue mice.

Hill KA, Halangoda A, Heinmoeller PW, Gonzalez K, Chitaphan C, Longmate J, Scaringe WA, Wang JC, Sommer SS. Hill KA, et al. Environ Mol Mutagen. 2005 Jun;45(5):442-54. doi: 10.1002/em.20119. Environ Mol Mutagen. 2005. PMID: 15690342

9

Methylation of CpG dinucleotides in the lacI gene of the Big Blue transgenic mouse.

You YH, Halangoda A, Buettner V, Hill K, Sommer S, Pfeifer G. You YH, et al. Mutat Res. 1998 Dec 3;420(1-3):55-65. doi: 10.1016/s1383-5718(98)00147-8. Mutat Res. 1998. PMID: 9838042

10

Heart tissue of harlequin (hq)/Big Blue mice has elevated reactive oxygen species without significant impact on the frequency and nature of point mutations in nuclear DNA.

Crabbe RA, Hill KA. Crabbe RA, et al. Among authors: hill ka. Mutat Res. 2010 Sep 10;691(1-2):64-71. doi: 10.1016/j.mrfmmm.2010.06.001. Epub 2010 Jun 10. Mutat Res. 2010. PMID: 20541563

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