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De novo design of a picomolar nonbasic 5-HT(1B) receptor antagonist.
Nugiel DA, Krumrine JR, Hill DC, Damewood JR Jr, Bernstein PR, Sobotka-Briner CD, Liu J, Zacco A, Pierson ME. Nugiel DA, et al. Among authors: hill dc. J Med Chem. 2010 Feb 25;53(4):1876-80. doi: 10.1021/jm901200t. J Med Chem. 2010. PMID: 20088516
Design, synthesis, and SAR of tachykinin antagonists: modulation of balance in NK(1)/NK(2) receptor antagonist activity.
Albert JS, Aharony D, Andisik D, Barthlow H, Bernstein PR, Bialecki RA, Dedinas R, Dembofsky BT, Hill D, Kirkland K, Koether GM, Kosmider BJ, Ohnmacht C, Palmer W, Potts W, Rumsey W, Shen L, Shenvi A, Sherwood S, Warwick PJ, Russell K. Albert JS, et al. J Med Chem. 2002 Aug 29;45(18):3972-83. doi: 10.1021/jm020094i. J Med Chem. 2002. PMID: 12190319
87 results