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Optimization of LpxC Inhibitors for Antibacterial Activity and Cardiovascular Safety.
ChemMedChem. 2019 Aug 20;14(16):1560-1572. doi: 10.1002/cmdc.201900287. Epub 2019 Aug 5.
ChemMedChem. 2019.
PMID: 31283109
Synthesis and spectrum of the neoglycoside ACHN-490.
Aggen JB, Armstrong ES, Goldblum AA, Dozzo P, Linsell MS, Gliedt MJ, Hildebrandt DJ, Feeney LA, Kubo A, Matias RD, Lopez S, Gomez M, Wlasichuk KB, Diokno R, Miller GH, Moser HE.
Aggen JB, et al. Among authors: hildebrandt dj.
Antimicrob Agents Chemother. 2010 Nov;54(11):4636-42. doi: 10.1128/AAC.00572-10. Epub 2010 Aug 30.
Antimicrob Agents Chemother. 2010.
PMID: 20805391
Free PMC article.
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Toward Overcoming Staphylococcus aureus Aminoglycoside Resistance Mechanisms with a Functionally Designed Neomycin Analogue.
Hanessian S, Giguère A, Grzyb J, Maianti JP, Saavedra OM, Aggen JB, Linsell MS, Goldblum AA, Hildebrandt DJ, Kane TR, Dozzo P, Gliedt MJ, Matias RD, Feeney LA, Armstrong ES.
Hanessian S, et al. Among authors: hildebrandt dj.
ACS Med Chem Lett. 2011 Sep 29;2(12):924-8. doi: 10.1021/ml200202y. eCollection 2011 Dec 8.
ACS Med Chem Lett. 2011.
PMID: 24900282
Free PMC article.
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Unraveling the Gentamicin Drug Product Complexity Reveals Variation in Microbiological Activities and Nephrotoxicity.
Bulman ZP, Cirz R, Hildebrandt D, Kane T, Rosario Z, Wlasichuk K, Park M, Andrews LD.
Bulman ZP, et al.
Antimicrob Agents Chemother. 2020 Aug 20;64(9):e00533-20. doi: 10.1128/AAC.00533-20. Print 2020 Aug 20.
Antimicrob Agents Chemother. 2020.
PMID: 32601158
Free PMC article.
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Toxicity modulation, resistance enzyme evasion, and A-site X-ray structure of broad-spectrum antibacterial neomycin analogs.
Maianti JP, Kanazawa H, Dozzo P, Matias RD, Feeney LA, Armstrong ES, Hildebrandt DJ, Kane TR, Gliedt MJ, Goldblum AA, Linsell MS, Aggen JB, Kondo J, Hanessian S.
Maianti JP, et al. Among authors: hildebrandt dj.
ACS Chem Biol. 2014 Sep 19;9(9):2067-73. doi: 10.1021/cb5003416. Epub 2014 Jul 14.
ACS Chem Biol. 2014.
PMID: 25019242
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Determination of equilibrium constant of amino carbamate adduct formation in sisomicin by a high pH based high performance liquid chromatography.
Wlasichuk KB, Tan L, Guo Y, Hildebrandt DJ, Zhang H, Karr DE, Schmidt DE Jr.
Wlasichuk KB, et al. Among authors: hildebrandt dj.
J Pharm Biomed Anal. 2015;111:126-30. doi: 10.1016/j.jpba.2015.03.033. Epub 2015 Apr 3.
J Pharm Biomed Anal. 2015.
PMID: 25880243
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Act with ethics. Sarbanes-Oxley's role in helping to ensure supply chain integrity.
Doyle FF, Graunke CL, Hildebrandt DJ, Otto RK, St George MC.
Doyle FF, et al. Among authors: hildebrandt dj.
Mater Manag Health Care. 2005 Jul;14(7):35-40.
Mater Manag Health Care. 2005.
PMID: 16146167
No abstract available.
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