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TNF-α-driven inflammation and mitochondrial dysfunction define the platelet hyperreactivity of aging.
Davizon-Castillo P, McMahon B, Aguila S, Bark D, Ashworth K, Allawzi A, Campbell RA, Montenont E, Nemkov T, D'Alessandro A, Clendenen N, Shih L, Sanders NA, Higa K, Cox A, Padilla-Romo Z, Hernandez G, Wartchow E, Trahan GD, Nozik-Grayck E, Jones K, Pietras EM, DeGregori J, Rondina MT, Di Paola J. Davizon-Castillo P, et al. Among authors: higa k. Blood. 2019 Aug 29;134(9):727-740. doi: 10.1182/blood.2019000200. Epub 2019 Jul 16. Blood. 2019. PMID: 31311815 Free PMC article.
Decoy fitness peaks, tumor suppression, and aging.
Higa KC, DeGregori J. Higa KC, et al. Aging Cell. 2019 Jun;18(3):e12938. doi: 10.1111/acel.12938. Epub 2019 Mar 8. Aging Cell. 2019. PMID: 30848555 Free PMC article.
PU.1 enforces quiescence and limits hematopoietic stem cell expansion during inflammatory stress.
Chavez JS, Rabe JL, Loeffler D, Higa KC, Hernandez G, Mills TS, Ahmed N, Gessner RL, Ke Z, Idler BM, Niño KE, Kim H, Myers JR, Stevens BM, Davizon-Castillo P, Jordan CT, Nakajima H, Ashton J, Welner RS, Schroeder T, DeGregori J, Pietras EM. Chavez JS, et al. J Exp Med. 2021 Jun 7;218(6):e20201169. doi: 10.1084/jem.20201169. J Exp Med. 2021. PMID: 33857288 Free PMC article.
Noteworthy Cardiac Literature From 2021: Coronary Guideline Change Without New Data, Heart Transplant Donation After Cardiac Death, Covid Effects on Global Cardiac Surgery, and Attempt to Improve Dissection Remodeling.
Hoffman JRH, Higa KC, Lin Y, Reece TB, Cleveland JC Jr, Aftab M, Rove JY. Hoffman JRH, et al. Semin Cardiothorac Vasc Anesth. 2022 Jun;26(2):154-161. doi: 10.1177/10892532221101298. Epub 2022 May 19. Semin Cardiothorac Vasc Anesth. 2022. PMID: 35591803
387 results