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SMARCAL1 is a dual regulator of innate immune signaling and PD-L1 expression that promotes tumor immune evasion.
Leuzzi G, Vasciaveo A, Taglialatela A, Chen X, Firestone TM, Hickman AR, Mao W, Thakar T, Vaitsiankova A, Huang JW, Cuella-Martin R, Hayward SB, Kesner JS, Ghasemzadeh A, Nambiar TS, Ho P, Rialdi A, Hebrard M, Li Y, Gao J, Gopinath S, Adeleke OA, Venters BJ, Drake CG, Baer R, Izar B, Guccione E, Keogh MC, Guerois R, Sun L, Lu C, Califano A, Ciccia A. Leuzzi G, et al. Among authors: hickman ar. Cell. 2024 Feb 15;187(4):861-881.e32. doi: 10.1016/j.cell.2024.01.008. Epub 2024 Jan 31. Cell. 2024. PMID: 38301646
Structural basis of histone H2A lysine 119 deubiquitination by Polycomb Repressive Deubiquitinase BAP1/ASXL1.
Thomas JF, Valencia-Sánchez MI, Tamburri S, Gloor SL, Rustichelli S, Godínez-López V, De Ioannes P, Lee R, Abini-Agbomson S, Gretarsson K, Burg JM, Hickman AR, Sun L, Gopinath S, Taylor H, Meiners MJ, Cheek MA, Rice W, Nudler E, Lu C, Keogh MC, Pasini D, Armache KJ. Thomas JF, et al. Among authors: hickman ar. bioRxiv [Preprint]. 2023 Feb 23:2023.02.23.529554. doi: 10.1101/2023.02.23.529554. bioRxiv. 2023. PMID: 36865140 Free PMC article. Updated. Preprint.
Cancer-associated DNA Hypermethylation of Polycomb Targets Requires DNMT3A Dual Recognition of Histone H2AK119 Ubiquitination and the Nucleosome Acidic Patch.
Gretarsson KH, Abini-Agbomson S, Gloor SL, Weinberg DN, McCuiston JL, Kumary VUS, Hickman AR, Sahu V, Lee R, Xu X, Lipieta N, Flashner S, Adeleke OA, Popova IK, Taylor HF, Noll K, Windham CL, Maryanski DN, Venters BJ, Nakagawa H, Keogh MC, Armache KJ, Lu C. Gretarsson KH, et al. Among authors: hickman ar. bioRxiv [Preprint]. 2024 Mar 20:2024.03.18.585588. doi: 10.1101/2024.03.18.585588. bioRxiv. 2024. PMID: 38562823 Free PMC article. Preprint.
Multivalent binding of the tardigrade Dsup protein to chromatin promotes yeast survival and longevity upon exposure to oxidative damage.
Aguilar R, Khan L, Arslanovic N, Birmingham K, Kasliwal K, Posnikoff S, Chakraborty U, Hickman AR, Watson R, Ezell RJ, Willis HE, Cowles MW, Garner R, Shim A, Gutierrez I, Marunde MR, Keogh MC, Tyler JK. Aguilar R, et al. Among authors: hickman ar. Res Sq [Preprint]. 2023 Jul 28:rs.3.rs-3182883. doi: 10.21203/rs.3.rs-3182883/v1. Res Sq. 2023. PMID: 37546815 Free PMC article. Preprint.
Structural basis of histone H2A lysine 119 deubiquitination by Polycomb repressive deubiquitinase BAP1/ASXL1.
Thomas JF, Valencia-Sánchez MI, Tamburri S, Gloor SL, Rustichelli S, Godínez-López V, De Ioannes P, Lee R, Abini-Agbomson S, Gretarsson K, Burg JM, Hickman AR, Sun L, Gopinath S, Taylor HF, Sun ZW, Ezell RJ, Vaidya A, Meiners MJ, Cheek MA, Rice WJ, Svetlov V, Nudler E, Lu C, Keogh MC, Pasini D, Armache KJ. Thomas JF, et al. Among authors: hickman ar. Sci Adv. 2023 Aug 9;9(32):eadg9832. doi: 10.1126/sciadv.adg9832. Epub 2023 Aug 9. Sci Adv. 2023. PMID: 37556531 Free PMC article.
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