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Development of a new comprehensive HIV-1 genotypic drug resistance assay for all commercially available reverse transcriptase, protease and integrase inhibitors in patients infected with group M HIV-1 strains.
Chrysostomou AC, Topcu C, Stylianou DC, Hezka J, Kostrikis LG. Chrysostomou AC, et al. Among authors: hezka j. Infect Genet Evol. 2020 Jul;81:104243. doi: 10.1016/j.meegid.2020.104243. Epub 2020 Feb 13. Infect Genet Evol. 2020. PMID: 32061896 Free article.
Molecular characterization of HIV type 1 strains from newly diagnosed patients in Cyprus (2007-2009) recovers multiple clades including unique recombinant strains and lack of transmitted drug resistance.
Kousiappa I, Achilleos C, Hezka J, Lazarou Y, Othonos K, Demetriades I, Kostrikis LG. Kousiappa I, et al. Among authors: hezka j. AIDS Res Hum Retroviruses. 2011 Nov;27(11):1183-99. doi: 10.1089/aid.2011.0060. Epub 2011 May 11. AIDS Res Hum Retroviruses. 2011. PMID: 21453134
HIV-1 transmission networks across Cyprus (2010-2012).
Kostrikis LG, Hezka J, Stylianou DC, Kostaki E, Andreou M, Kousiappa I, Paraskevis D, Demetriades I. Kostrikis LG, et al. Among authors: hezka j. PLoS One. 2018 Apr 23;13(4):e0195660. doi: 10.1371/journal.pone.0195660. eCollection 2018. PLoS One. 2018. PMID: 29684083 Free PMC article.
Patterns of transmitted HIV drug resistance in Europe vary by risk group.
Frentz D, van de Vijver D, Abecasis A, Albert J, Hamouda O, Jørgensen L, Kücherer C, Struck D, Schmit JC, Vercauteren J, Asjö B, Balotta C, Bergin C, Beshkov D, Camacho R, Clotet B, Griskevicius A, Grossman Z, Horban A, Kolupajeva T, Korn K, Kostrikis L, Linka KL, Nielsen C, Otelea D, Paraskevis D, Paredes R, Poljak M, Puchhammer-Stöckl E, Sönnerborg A, Stanekova D, Stanojevic M, Vandamme AM, Boucher C, Wensing A; SPREAD Programme. Frentz D, et al. PLoS One. 2014 Apr 10;9(4):e94495. doi: 10.1371/journal.pone.0094495. eCollection 2014. PLoS One. 2014. PMID: 24721998 Free PMC article.
Increase in transmitted resistance to non-nucleoside reverse transcriptase inhibitors among newly diagnosed HIV-1 infections in Europe.
Frentz D, Van de Vijver DA, Abecasis AB, Albert J, Hamouda O, Jørgensen LB, Kücherer C, Struck D, Schmit JC, Vercauteren J, Åsjö B, Balotta C, Beshkov D, Camacho RJ, Clotet B, Coughlan S, Griskevicius A, Grossman Z, Horban A, Kolupajeva T, Korn K, Kostrikis LG, Liitsola K, Linka M, Nielsen C, Otelea D, Paraskevis D, Paredes R, Poljak M, Puchhammer-Stöckl E, Sönnerborg A, Stanekova D, Stanojevic M, Van Wijngaerden E, Wensing AM, Boucher CA; SPREAD Programme. Frentz D, et al. BMC Infect Dis. 2014 Jul 21;14:407. doi: 10.1186/1471-2334-14-407. BMC Infect Dis. 2014. PMID: 25047543 Free PMC article. Clinical Trial.
Transmission of HIV Drug Resistance and the Predicted Effect on Current First-line Regimens in Europe.
Hofstra LM, Sauvageot N, Albert J, Alexiev I, Garcia F, Struck D, Van de Vijver DAMC, Åsjö B, Beshkov D, Coughlan S, Descamps D, Griskevicius A, Hamouda O, Horban A, Van Kasteren M, Kolupajeva T, Kostrikis LG, Liitsola K, Linka M, Mor O, Nielsen C, Otelea D, Paraskevis D, Paredes R, Poljak M, Puchhammer-Stöckl E, Sönnerborg A, Staneková D, Stanojevic M, Van Laethem K, Zazzi M, Zidovec Lepej S, Boucher CAB, Schmit JC, Wensing AMJ; SPREAD Program; Puchhammer-Stockl E, Sarcletti M, Schmied B, Geit M, Balluch G, Vandamme AM, Vercauteren J, Derdelinckx I, Sasse A, Bogaert M, Ceunen H, De Roo A, De Wit S, Echahidi F, Fransen K, Goffard JC, Goubau P, Goudeseune E, Yombi JC, Lacor P, Liesnard C, Moutschen M, Pierard D, Rens R, Schrooten Y, Vaira D, Vandekerckhove LPR, Van den Heuvel A, Van Der Gucht B, Van Ranst M, Van Wijngaerden E, Vandercam B, Vekemans M, Verhofstede C, Clumeck N, Van Laethem K, Beshkov D, Alexiev I, Lepej SZ, Begovac J, Kostrikis L, Demetriades I, Kousiappa I, Demetriou V, Hezka J, Linka M, Maly M, Machala L, Nielsen C, Jørgensen LB, Gerstoft J, Mathiesen L, Pedersen C, Nielsen H, Laursen A, Kvinesdal B, Liitsola K, Ristola M, Suni J, Sutinen J, Descamps D, Ass… See abstract for full author list ➔ Hofstra LM, et al. Among authors: hezka j. Clin Infect Dis. 2016 Mar 1;62(5):655-663. doi: 10.1093/cid/civ963. Epub 2015 Nov 29. Clin Infect Dis. 2016. PMID: 26620652 Free PMC article.
Cellular HIV type 1 DNA levels are equivalent among drug-sensitive and drug-resistant strains in newly diagnosed and antiretroviral naive patients.
Antoniadou ZA, Hezka J, Kousiappa I, Mamais I, Skoura L, Pilalas D, Metallidis S, Nicolaidis P, Malisiovas N, Kostrikis LG. Antoniadou ZA, et al. Among authors: hezka j. AIDS Res Hum Retroviruses. 2014 Mar;30(3):266-71. doi: 10.1089/AID.2013.0160. Epub 2013 Oct 9. AIDS Res Hum Retroviruses. 2014. PMID: 24025041
Treatment-associated polymorphisms in protease are significantly associated with higher viral load and lower CD4 count in newly diagnosed drug-naive HIV-1 infected patients.
Theys K, Deforche K, Vercauteren J, Libin P, van de Vijver DA, Albert J, Asjö B, Balotta C, Bruckova M, Camacho RJ, Clotet B, Coughlan S, Grossman Z, Hamouda O, Horban A, Korn K, Kostrikis LG, Kücherer C, Nielsen C, Paraskevis D, Poljak M, Puchhammer-Stockl E, Riva C, Ruiz L, Liitsola K, Schmit JC, Schuurman R, Sönnerborg A, Stanekova D, Stanojevic M, Struck D, Van Laethem K, Wensing AM, Boucher CA, Vandamme AM; SPREAD-programme. Theys K, et al. Retrovirology. 2012 Oct 3;9:81. doi: 10.1186/1742-4690-9-81. Retrovirology. 2012. PMID: 23031662 Free PMC article.
13 results