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Autophagy in intra-hepatic cholangiocarcinoma.
Huang JL, Hezel AF. Huang JL, et al. Among authors: hezel af. Autophagy. 2012 Jul 1;8(7):1148-9. doi: 10.4161/auto.20647. Epub 2012 Jul 1. Autophagy. 2012. PMID: 22751196 Free PMC article.
Kras(G12D) and p53 mutation cause primary intrahepatic cholangiocarcinoma.
O'Dell MR, Huang JL, Whitney-Miller CL, Deshpande V, Rothberg P, Grose V, Rossi RM, Zhu AX, Land H, Bardeesy N, Hezel AF. O'Dell MR, et al. Among authors: hezel af. Cancer Res. 2012 Mar 15;72(6):1557-67. doi: 10.1158/0008-5472.CAN-11-3596. Epub 2012 Jan 20. Cancer Res. 2012. PMID: 22266220 Free PMC article.
FOSL1 promotes cholangiocarcinoma via transcriptional effectors that could be therapeutically targeted.
Vallejo A, Erice O, Entrialgo-Cadierno R, Feliu I, Guruceaga E, Perugorria MJ, Olaizola P, Muggli A, Macaya I, O'Dell M, Ruiz-Fernandez de Cordoba B, Ortiz-Espinosa S, Hezel AF, Arozarena I, Lecanda F, Avila MA, Fernandez-Barrena MG, Evert M, Ponz-Sarvise M, Calvisi DF, Banales JM, Vicent S. Vallejo A, et al. Among authors: hezel af. J Hepatol. 2021 Aug;75(2):363-376. doi: 10.1016/j.jhep.2021.03.028. Epub 2021 Apr 20. J Hepatol. 2021. PMID: 33887357 Free article.
Arid1a mutation suppresses TGF-β signaling and induces cholangiocarcinoma.
Guo B, Friedland SC, Alexander W, Myers JA, Wang W, O'Dell MR, Getman M, Whitney-Miller CL, Agostini-Vulaj D, Huber AR, Mello SS, Vertino PM, Land HK, Steiner LA, Hezel AF. Guo B, et al. Among authors: hezel af. Cell Rep. 2022 Aug 30;40(9):111253. doi: 10.1016/j.celrep.2022.111253. Cell Rep. 2022. PMID: 36044839 Free PMC article.
Phase II study of gemcitabine, oxaliplatin in combination with panitumumab in KRAS wild-type unresectable or metastatic biliary tract and gallbladder cancer.
Hezel AF, Noel MS, Allen JN, Abrams TA, Yurgelun M, Faris JE, Goyal L, Clark JW, Blaszkowsky LS, Murphy JE, Zheng H, Khorana AA, Connolly GC, Hyrien O, Baran A, Herr M, Ng K, Sheehan S, Harris DJ, Regan E, Borger DR, Iafrate AJ, Fuchs C, Ryan DP, Zhu AX. Hezel AF, et al. Br J Cancer. 2014 Jul 29;111(3):430-6. doi: 10.1038/bjc.2014.343. Epub 2014 Jun 24. Br J Cancer. 2014. PMID: 24960403 Free PMC article. Clinical Trial.
Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer.
Saha SK, Parachoniak CA, Ghanta KS, Fitamant J, Ross KN, Najem MS, Gurumurthy S, Akbay EA, Sia D, Cornella H, Miltiadous O, Walesky C, Deshpande V, Zhu AX, Hezel AF, Yen KE, Straley KS, Travins J, Popovici-Muller J, Gliser C, Ferrone CR, Apte U, Llovet JM, Wong KK, Ramaswamy S, Bardeesy N. Saha SK, et al. Among authors: hezel af. Nature. 2014 Sep 4;513(7516):110-4. doi: 10.1038/nature13441. Epub 2014 Jul 2. Nature. 2014. PMID: 25043045 Free PMC article.
Genetics and Biology of Pancreatic Ductal Adenocarcinoma.
Dunne RF, Hezel AF. Dunne RF, et al. Among authors: hezel af. Hematol Oncol Clin North Am. 2015 Aug;29(4):595-608. doi: 10.1016/j.hoc.2015.04.003. Epub 2015 Jun 10. Hematol Oncol Clin North Am. 2015. PMID: 26226899 Free PMC article. Review.
76 results