Heyes JA - Search Results

1

RNAi-mediated gene silencing in non-human primates.

Zimmermann TS, Lee AC, Akinc A, Bramlage B, Bumcrot D, Fedoruk MN, Harborth J, Heyes JA, Jeffs LB, John M, Judge AD, Lam K, McClintock K, Nechev LV, Palmer LR, Racie T, Röhl I, Seiffert S, Shanmugam S, Sood V, Soutschek J, Toudjarska I, Wheat AJ, Yaworski E, Zedalis W, Koteliansky V, Manoharan M, Vornlocher HP, MacLachlan I. Zimmermann TS, et al. Among authors: heyes ja. Nature. 2006 May 4;441(7089):111-4. doi: 10.1038/nature04688. Epub 2006 Mar 26. Nature. 2006. PMID: 16565705

2

Stabilized plasmid-lipid particles containing PEG-diacylglycerols exhibit extended circulation lifetimes and tumor selective gene expression.

Ambegia E, Ansell S, Cullis P, Heyes J, Palmer L, MacLachlan I. Ambegia E, et al. Biochim Biophys Acta. 2005 May 20;1669(2):155-63. doi: 10.1016/j.bbamem.2005.02.001. Epub 2005 Feb 24. Biochim Biophys Acta. 2005. PMID: 15893518 Free article.

3

Cationic lipid saturation influences intracellular delivery of encapsulated nucleic acids.

Heyes J, Palmer L, Bremner K, MacLachlan I. Heyes J, et al. J Control Release. 2005 Oct 3;107(2):276-87. doi: 10.1016/j.jconrel.2005.06.014. J Control Release. 2005. PMID: 16054724

4

Synthesis and characterization of novel poly(ethylene glycol)-lipid conjugates suitable for use in drug delivery.

Heyes J, Hall K, Tailor V, Lenz R, MacLachlan I. Heyes J, et al. J Control Release. 2006 May 15;112(2):280-90. doi: 10.1016/j.jconrel.2006.02.012. Epub 2006 Mar 6. J Control Release. 2006. PMID: 16603272

5

Lipid encapsulation enables the effective systemic delivery of polyplex plasmid DNA.

Heyes J, Palmer L, Chan K, Giesbrecht C, Jeffs L, MacLachlan I. Heyes J, et al. Mol Ther. 2007 Apr;15(4):713-20. doi: 10.1038/sj.mt.6300101. Epub 2007 Feb 13. Mol Ther. 2007. PMID: 17299407 Free article.

6

Ligand conjugate SAR and enhanced delivery in NHP.

Holland RJ, Lam K, Ye X, Martin AD, Wood MC, Palmer L, Fraser D, McClintock K, Majeski S, Jarosz A, Lee ACH, Thi EP, Judge A, Heyes J. Holland RJ, et al. Mol Ther. 2021 Oct 6;29(10):2910-2919. doi: 10.1016/j.ymthe.2021.06.002. Epub 2021 Jun 4. Mol Ther. 2021. PMID: 34091052 Free PMC article.

7

Combination treatment of mannose and GalNAc conjugated small interfering RNA protects against lethal Marburg virus infection.

Ye X, Holland R, Wood M, Pasetka C, Palmer L, Samaridou E, McClintock K, Borisevich V, Geisbert TW, Cross RW, Heyes J. Ye X, et al. Mol Ther. 2023 Jan 4;31(1):269-281. doi: 10.1016/j.ymthe.2022.09.009. Epub 2022 Sep 15. Mol Ther. 2023. PMID: 36114672 Free PMC article.

8

Unsaturated, Trialkyl Ionizable Lipids are Versatile Lipid-Nanoparticle Components for Therapeutic and Vaccine Applications.

Lam K, Leung A, Martin A, Wood M, Schreiner P, Palmer L, Daly O, Zhao W, McClintock K, Heyes J. Lam K, et al. Adv Mater. 2023 Apr;35(15):e2209624. doi: 10.1002/adma.202209624. Epub 2023 Mar 5. Adv Mater. 2023. PMID: 36680477

9

Optimizing Lipid Nanoparticles for Delivery in Primates.

Lam K, Schreiner P, Leung A, Stainton P, Reid S, Yaworski E, Lutwyche P, Heyes J. Lam K, et al. Adv Mater. 2023 Jun;35(26):e2211420. doi: 10.1002/adma.202211420. Epub 2023 May 11. Adv Mater. 2023. PMID: 36972555

10

Silicon Ether Ionizable Lipids Enable Potent mRNA Lipid Nanoparticles with Rapid Tissue Clearance.

Holland R, Lam K, Jeng S, McClintock K, Palmer L, Schreiner P, Wood M, Zhao W, Heyes J. Holland R, et al. ACS Nano. 2024 Apr 16;18(15):10374-10387. doi: 10.1021/acsnano.3c09028. Epub 2024 Apr 3. ACS Nano. 2024. PMID: 38567845 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

27 results

Search Page