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Precision medicine and lymphoma.
Heward JA, Kumar EA, Korfi K, Okosun J, Fitzgibbon J. Heward JA, et al. Curr Opin Hematol. 2018 Jul;25(4):329-334. doi: 10.1097/MOH.0000000000000437. Curr Opin Hematol. 2018. PMID: 29738334 Review.
Epigenetic dysregulation in follicular lymphoma.
Araf S, Okosun J, Koniali L, Fitzgibbon J, Heward J. Araf S, et al. Epigenomics. 2016 Jan;8(1):77-84. doi: 10.2217/epi.15.96. Epub 2015 Dec 23. Epigenomics. 2016. PMID: 26698557 Free PMC article. Review.
Genomic profiling reveals spatial intra-tumor heterogeneity in follicular lymphoma.
Araf S, Wang J, Korfi K, Pangault C, Kotsiou E, Rio-Machin A, Rahim T, Heward J, Clear A, Iqbal S, Davies JK, Johnson P, Calaminici M, Montoto S, Auer R, Chelala C, Gribben JG, Graham TA, Fest T, Fitzgibbon J, Okosun J. Araf S, et al. Leukemia. 2018 May;32(5):1261-1265. doi: 10.1038/s41375-018-0043-y. Epub 2018 Feb 8. Leukemia. 2018. PMID: 29568095 Free PMC article. No abstract available.
Correction: Genomic profiling reveals spatial intra-tumor heterogeneity in follicular lymphoma.
Araf S, Wang J, Korfi K, Pangault C, Kotsiou E, Rio-Machin A, Rahim T, Heward J, Clear A, Iqbal S, Davies JK, Johnson P, Calaminici M, Montoto S, Auer R, Chelala C, Gribben JG, Graham TA, Fest T, Fitzgibbon J, Okosun J. Araf S, et al. Leukemia. 2019 Jun;33(6):1540. doi: 10.1038/s41375-019-0425-9. Leukemia. 2019. PMID: 30903015 Free PMC article.
KDM5 inhibition offers a novel therapeutic strategy for the treatment of KMT2D mutant lymphomas.
Heward J, Konali L, D'Avola A, Close K, Yeomans A, Philpott M, Dunford J, Rahim T, Al Seraihi AF, Wang J, Korfi K, Araf S, Iqbal S, Bewicke-Copley F, Kumar E, Barisic D, Calaminici M, Clear A, Gribben J, Johnson P, Neve R, Cutillas P, Okosun J, Oppermann U, Melnick A, Packham G, Fitzgibbon J. Heward J, et al. Blood. 2021 Aug 5;138(5):370-381. doi: 10.1182/blood.2020008743. Blood. 2021. PMID: 33786580 Free PMC article.
GATA2 monoallelic expression underlies reduced penetrance in inherited GATA2-mutated MDS/AML.
Al Seraihi AF, Rio-Machin A, Tawana K, Bödör C, Wang J, Nagano A, Heward JA, Iqbal S, Best S, Lea N, McLornan D, Kozyra EJ, Wlodarski MW, Niemeyer CM, Scott H, Hahn C, Ellison A, Tummala H, Cardoso SR, Vulliamy T, Dokal I, Butler T, Smith M, Cavenagh J, Fitzgibbon J. Al Seraihi AF, et al. Among authors: heward ja. Leukemia. 2018 Nov;32(11):2502-2507. doi: 10.1038/s41375-018-0134-9. Epub 2018 Apr 19. Leukemia. 2018. PMID: 29749400 Free PMC article. No abstract available.
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