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Noncoding regions are the main source of targetable tumor-specific antigens.
Laumont CM, Vincent K, Hesnard L, Audemard É, Bonneil É, Laverdure JP, Gendron P, Courcelles M, Hardy MP, Côté C, Durette C, St-Pierre C, Benhammadi M, Lanoix J, Vobecky S, Haddad E, Lemieux S, Thibault P, Perreault C. Laumont CM, et al. Among authors: hesnard l. Sci Transl Med. 2018 Dec 5;10(470):eaau5516. doi: 10.1126/scitranslmed.aau5516. Sci Transl Med. 2018. PMID: 30518613
Atypical acute myeloid leukemia-specific transcripts generate shared and immunogenic MHC class-I-associated epitopes.
Ehx G, Larouche JD, Durette C, Laverdure JP, Hesnard L, Vincent K, Hardy MP, Thériault C, Rulleau C, Lanoix J, Bonneil E, Feghaly A, Apavaloaei A, Noronha N, Laumont CM, Delisle JS, Vago L, Hébert J, Sauvageau G, Lemieux S, Thibault P, Perreault C. Ehx G, et al. Among authors: hesnard l. Immunity. 2021 Apr 13;54(4):737-752.e10. doi: 10.1016/j.immuni.2021.03.001. Epub 2021 Mar 18. Immunity. 2021. PMID: 33740418 Free article.
Induced pluripotent stem cells display a distinct set of MHC I-associated peptides shared by human cancers.
Apavaloaei A, Hesnard L, Hardy MP, Benabdallah B, Ehx G, Thériault C, Laverdure JP, Durette C, Lanoix J, Courcelles M, Noronha N, Chauhan KD, Lemieux S, Beauséjour C, Bhatia M, Thibault P, Perreault C. Apavaloaei A, et al. Among authors: hesnard l. Cell Rep. 2022 Aug 16;40(7):111241. doi: 10.1016/j.celrep.2022.111241. Cell Rep. 2022. PMID: 35977509 Free article.
Breast cancer immunopeptidomes contain numerous shared tumor antigens.
Kina E, Laverdure JP, Durette C, Lanoix J, Courcelles M, Zhao Q, Apavaloaei A, Larouche JD, Hardy MP, Vincent K, Gendron P, Hesnard L, Thériault C, Ruiz Cuevas MV, Ehx G, Thibault P, Perreault C. Kina E, et al. Among authors: hesnard l. J Clin Invest. 2024 Jan 2;134(1):e166740. doi: 10.1172/JCI166740. J Clin Invest. 2024. PMID: 37906288 Free PMC article.
11 results