Hesketh GG - Search Results

1

VARP is recruited on to endosomes by direct interaction with retromer, where together they function in export to the cell surface.

Hesketh GG, Pérez-Dorado I, Jackson LP, Wartosch L, Schäfer IB, Gray SR, McCoy AJ, Zeldin OB, Garman EF, Harbour ME, Evans PR, Seaman MNJ, Luzio JP, Owen DJ. Hesketh GG, et al. Dev Cell. 2014 Jun 9;29(5):591-606. doi: 10.1016/j.devcel.2014.04.010. Epub 2014 May 22. Dev Cell. 2014. PMID: 24856514 Free PMC article.

2

RME-8 coordinates the activity of the WASH complex with the function of the retromer SNX dimer to control endosomal tubulation.

Freeman CL, Hesketh G, Seaman MN. Freeman CL, et al. J Cell Sci. 2014 May 1;127(Pt 9):2053-70. doi: 10.1242/jcs.144659. Epub 2014 Mar 18. J Cell Sci. 2014. PMID: 24643499 Free PMC article.

3

The binding of Varp to VAMP7 traps VAMP7 in a closed, fusogenically inactive conformation.

Schäfer IB, Hesketh GG, Bright NA, Gray SR, Pryor PR, Evans PR, Luzio JP, Owen DJ. Schäfer IB, et al. Among authors: hesketh gg. Nat Struct Mol Biol. 2012 Dec;19(12):1300-9. doi: 10.1038/nsmb.2414. Epub 2012 Oct 28. Nat Struct Mol Biol. 2012. PMID: 23104059 Free PMC article.

4

BLOC-1 and BLOC-3 regulate VAMP7 cycling to and from melanosomes via distinct tubular transport carriers.

Dennis MK, Delevoye C, Acosta-Ruiz A, Hurbain I, Romao M, Hesketh GG, Goff PS, Sviderskaya EV, Bennett DC, Luzio JP, Galli T, Owen DJ, Raposo G, Marks MS. Dennis MK, et al. Among authors: hesketh gg. J Cell Biol. 2016 Aug 1;214(3):293-308. doi: 10.1083/jcb.201605090. J Cell Biol. 2016. PMID: 27482051 Free PMC article.

5

The Lysosome and Intracellular Signalling.

Hesketh GG, Wartosch L, Davis LJ, Bright NA, Luzio JP. Hesketh GG, et al. Prog Mol Subcell Biol. 2018;57:151-180. doi: 10.1007/978-3-319-96704-2_6. Prog Mol Subcell Biol. 2018. PMID: 30097775 Review.

6

Rag GTPases and phosphatidylinositol 3-phosphate mediate recruitment of the AP-5/SPG11/SPG15 complex.

Hirst J, Hesketh GG, Gingras AC, Robinson MS. Hirst J, et al. Among authors: hesketh gg. J Cell Biol. 2021 Feb 1;220(2):e202002075. doi: 10.1083/jcb.202002075. J Cell Biol. 2021. PMID: 33464297 Free PMC article.

7

Myosin VI facilitates connexin 43 gap junction accretion.

Waxse BJ, Sengupta P, Hesketh GG, Lippincott-Schwartz J, Buss F. Waxse BJ, et al. Among authors: hesketh gg. J Cell Sci. 2017 Mar 1;130(5):827-840. doi: 10.1242/jcs.199083. Epub 2017 Jan 17. J Cell Sci. 2017. PMID: 28096472 Free PMC article.

8

Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.

Hunter MR, Hesketh GG, Benedyk TH, Gingras AC, Graham SC. Hunter MR, et al. Among authors: hesketh gg. J Mol Biol. 2018 Jul 6;430(14):2153-2163. doi: 10.1016/j.jmb.2018.05.019. Epub 2018 May 17. J Mol Biol. 2018. PMID: 29778605 Free PMC article.

9

Endosomal LC3C-pathway selectively targets plasma membrane cargo for autophagic degradation.

Coelho PP, Hesketh GG, Pedersen A, Kuzmin E, Fortier AN, Bell ES, Ratcliffe CDH, Gingras AC, Park M. Coelho PP, et al. Among authors: hesketh gg. Nat Commun. 2022 Jul 2;13(1):3812. doi: 10.1038/s41467-022-31465-3. Nat Commun. 2022. PMID: 35780247 Free PMC article.

10

The GATOR-Rag GTPase pathway inhibits mTORC1 activation by lysosome-derived amino acids.

Hesketh GG, Papazotos F, Pawling J, Rajendran D, Knight JDR, Martinez S, Taipale M, Schramek D, Dennis JW, Gingras AC. Hesketh GG, et al. Science. 2020 Oct 16;370(6514):351-356. doi: 10.1126/science.aaz0863. Science. 2020. PMID: 33060361

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