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Genetic insights into biological mechanisms governing human ovarian ageing.
Ruth KS, Day FR, Hussain J, Martínez-Marchal A, Aiken CE, Azad A, Thompson DJ, Knoblochova L, Abe H, Tarry-Adkins JL, Gonzalez JM, Fontanillas P, Claringbould A, Bakker OB, Sulem P, Walters RG, Terao C, Turon S, Horikoshi M, Lin K, Onland-Moret NC, Sankar A, Hertz EPT, Timshel PN, Shukla V, Borup R, Olsen KW, Aguilera P, Ferrer-Roda M, Huang Y, Stankovic S, Timmers PRHJ, Ahearn TU, Alizadeh BZ, Naderi E, Andrulis IL, Arnold AM, Aronson KJ, Augustinsson A, Bandinelli S, Barbieri CM, Beaumont RN, Becher H, Beckmann MW, Benonisdottir S, Bergmann S, Bochud M, Boerwinkle E, Bojesen SE, Bolla MK, Boomsma DI, Bowker N, Brody JA, Broer L, Buring JE, Campbell A, Campbell H, Castelao JE, Catamo E, Chanock SJ, Chenevix-Trench G, Ciullo M, Corre T, Couch FJ, Cox A, Crisponi L, Cross SS, Cucca F, Czene K, Smith GD, de Geus EJCN, de Mutsert R, De Vivo I, Demerath EW, Dennis J, Dunning AM, Dwek M, Eriksson M, Esko T, Fasching PA, Faul JD, Ferrucci L, Franceschini N, Frayling TM, Gago-Dominguez M, Mezzavilla M, García-Closas M, Gieger C, Giles GG, Grallert H, Gudbjartsson DF, Gudnason V, Guénel P, Haiman CA, Håkansson N, Hall P, Hayward C, He C, He W, Heiss G, Høffding MK, Hopper JL, Hotte… See abstract for full author list ➔ Ruth KS, et al. Among authors: hertz ept. Nature. 2021 Aug;596(7872):393-397. doi: 10.1038/s41586-021-03779-7. Epub 2021 Aug 4. Nature. 2021. PMID: 34349265 Free PMC article.
Localization of PP2A-B56 to centromeres in Drosophila.
Hertz EPT, Nilsson J. Hertz EPT, et al. Cell Cycle. 2017 Aug 3;16(15):1385-1386. doi: 10.1080/15384101.2017.1337986. Epub 2017 Jul 19. Cell Cycle. 2017. PMID: 28723235 Free PMC article. No abstract available.
The SUMO-NIP45 pathway processes toxic DNA catenanes to prevent mitotic failure.
Hertz EPT, Vega IA, Kruse T, Wang Y, Hendriks IA, Bizard AH, Eugui-Anta A, Hay RT, Nielsen ML, Nilsson J, Hickson ID, Mailand N. Hertz EPT, et al. Nat Struct Mol Biol. 2023 Sep;30(9):1303-1313. doi: 10.1038/s41594-023-01045-0. Epub 2023 Jul 20. Nat Struct Mol Biol. 2023. PMID: 37474739 Free PMC article.
Chemogenetic profiling reveals PP2A-independent cytotoxicity of proposed PP2A activators iHAP1 and DT-061.
Vit G, Duro J, Rajendraprasad G, Hertz EPT, Holland LKK, Weisser MB, McEwan BC, Lopez-Mendez B, Sotelo-Parrilla P, Jeyaprakash AA, Montoya G, Mailand N, Maeda K, Kettenbach A, Barisic M, Nilsson J. Vit G, et al. Among authors: hertz ept. EMBO J. 2022 Jul 18;41(14):e110611. doi: 10.15252/embj.2022110611. Epub 2022 Jun 13. EMBO J. 2022. PMID: 35695070 Free PMC article.
SCAI promotes error-free repair of DNA interstrand crosslinks via the Fanconi anemia pathway.
Schubert L, Hendriks IA, Hertz EPT, Wu W, Sellés-Baiget S, Hoffmann S, Viswalingam KS, Gallina I, Pentakota S, Benedict B, Johansen J, Apelt K, Luijsterburg MS, Rasmussen S, Lisby M, Liu Y, Nielsen ML, Mailand N, Duxin JP. Schubert L, et al. Among authors: hertz ept. EMBO Rep. 2022 Apr 5;23(4):e53639. doi: 10.15252/embr.202153639. Epub 2022 Feb 14. EMBO Rep. 2022. PMID: 35156773 Free PMC article.
A complex of BRCA2 and PP2A-B56 is required for DNA repair by homologous recombination.
Ambjørn SM, Duxin JP, Hertz EPT, Nasa I, Duro J, Kruse T, Lopez-Mendez B, Rymarczyk B, Cressey LE, van Overeem Hansen T, Kettenbach AN, Oestergaard VH, Lisby M, Nilsson J. Ambjørn SM, et al. Among authors: hertz ept. Nat Commun. 2021 Sep 30;12(1):5748. doi: 10.1038/s41467-021-26079-0. Nat Commun. 2021. PMID: 34593815 Free PMC article.
13 results