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European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation.
Budu-Aggrey A, Kilanowski A, Sobczyk MK; 23andMe Research Team; Shringarpure SS, Mitchell R, Reis K, Reigo A; Estonian Biobank Research Team; Mägi R, Nelis M, Tanaka N, Brumpton BM, Thomas LF, Sole-Navais P, Flatley C, Espuela-Ortiz A, Herrera-Luis E, Lominchar JVT, Bork-Jensen J, Marenholz I, Arnau-Soler A, Jeong A, Fawcett KA, Baurecht H, Rodriguez E, Alves AC, Kumar A, Sleiman PM, Chang X, Medina-Gomez C, Hu C, Xu CJ, Qi C, El-Heis S, Titcombe P, Antoun E, Fadista J, Wang CA, Thiering E, Wu B, Kress S, Kothalawala DM, Kadalayil L, Duan J, Zhang H, Hadebe S, Hoffmann T, Jorgenson E, Choquet H, Risch N, Njølstad P, Andreassen OA, Johansson S, Almqvist C, Gong T, Ullemar V, Karlsson R, Magnusson PKE, Szwajda A, Burchard EG, Thyssen JP, Hansen T, Kårhus LL, Dantoft TM, Jeanrenaud ACSN, Ghauri A, Arnold A, Homuth G, Lau S, Nöthen MM, Hübner N, Imboden M, Visconti A, Falchi M, Bataille V, Hysi P, Ballardini N, Boomsma DI, Hottenga JJ, Müller-Nurasyid M, Ahluwalia TS, Stokholm J, Chawes B, Schoos AM, Esplugues A, Bustamante M, Raby B, Arshad S, German C, Esko T, Milani LA, Metspalu A, Terao C, Abuabara K, Løset M, Hveem K, Jacobsson B, Pino-Yanes M, Strachan DP, Grarup N, Linne… See abstract for full author list ➔ Budu-Aggrey A, et al. Among authors: herrera luis e. Nat Commun. 2023 Oct 4;14(1):6172. doi: 10.1038/s41467-023-41180-2. Nat Commun. 2023. PMID: 37794016 Free PMC article.
17q21 variant increases the risk of exacerbations in asthmatic children despite inhaled corticosteroids use.
Farzan N, Vijverberg SJ, Hernandez-Pacheco N, Bel EHD, Berce V, Bønnelykke K, Bisgaard H, Burchard EG, Canino G, Celedón JC, Chew FT, Chiang WC, Cloutier MM, Forno E, Francis B, Hawcutt DB, Herrera-Luis E, Kabesch M, Karimi L, Melén E, Mukhopadhyay S, Merid SK, Palmer CN, Pino-Yanes M, Pirmohamed M, Potočnik U, Repnik K, Schieck M, Sevelsted A, Sio YY, Smyth RL, Soares P, Söderhäll C, Tantisira KG, Tavendale R, Tse SM, Turner S, Verhamme KM, Maitland-van der Zee AH. Farzan N, et al. Allergy. 2018 Oct;73(10):2083-2088. doi: 10.1111/all.13499. Epub 2018 Jul 9. Allergy. 2018. PMID: 29885281 Free PMC article.
Role of genomics in asthma exacerbations.
Herrera-Luis E, Hernandez-Pacheco N, Vijverberg SJ, Flores C, Pino-Yanes M. Herrera-Luis E, et al. Curr Opin Pulm Med. 2019 Jan;25(1):101-112. doi: 10.1097/MCP.0000000000000533. Curr Opin Pulm Med. 2019. PMID: 30334825 Review.
A genome-wide association study of asthma hospitalizations in adults.
Yan Q, Forno E, Herrera-Luis E, Pino-Yanes M, Yang G, Oh S, Acosta-Pérez E, Hu D, Eng C, Huntsman S, Rodriguez-Santana JR, Cloutier MM, Canino G, Burchard EG, Chen W, Celedón JC. Yan Q, et al. J Allergy Clin Immunol. 2021 Mar;147(3):933-940. doi: 10.1016/j.jaci.2020.08.020. Epub 2020 Sep 2. J Allergy Clin Immunol. 2021. PMID: 32890573 Free PMC article.
A deoxyribonuclease 1-like 3 genetic variant associates with asthma exacerbations.
Herrera-Luis E, Lorenzo-Diaz F, Samedy-Bates LA, Eng C, Villar J, Rodriguez-Santana JR, Burchard EG, Pino-Yanes M. Herrera-Luis E, et al. J Allergy Clin Immunol. 2021 Mar;147(3):1095-1097.e10. doi: 10.1016/j.jaci.2020.09.027. Epub 2020 Oct 6. J Allergy Clin Immunol. 2021. PMID: 33035569 Free PMC article.
A genome-wide association study of severe asthma exacerbations in Latino children and adolescents.
Yan Q, Forno E, Herrera-Luis E, Pino-Yanes M, Qi C, Rios R, Han YY, Kim S, Oh S, Acosta-Pérez E, Zhang R, Hu D, Eng C, Huntsman S, Avila L, Boutaoui N, Cloutier MM, Soto-Quiros ME, Xu CJ, Weiss ST, Lasky-Su J, Kiedrowski MR, Figueiredo C, Bomberger J, Barreto ML, Canino G, Chen W, Koppelman GH, Burchard EG, Celedón JC. Yan Q, et al. Eur Respir J. 2021 Apr 1;57(4):2002693. doi: 10.1183/13993003.02693-2020. Print 2021 Apr. Eur Respir J. 2021. PMID: 33093117 Free PMC article.
Genome-wide association study of asthma exacerbations despite inhaled corticosteroid use.
Hernandez-Pacheco N, Vijverberg SJ, Herrera-Luis E, Li J, Sio YY, Granell R, Corrales A, Maroteau C, Lethem R, Perez-Garcia J, Farzan N, Repnik K, Gorenjak M, Soares P, Karimi L, Schieck M, Pérez-Méndez L, Berce V, Tavendale R, Eng C, Sardon O, Kull I, Mukhopadhyay S, Pirmohamed M, Verhamme KMC, Burchard EG, Kabesch M, Hawcutt DB, Melén E, Potočnik U, Chew FT, Tantisira KG, Turner S, Palmer CN, Flores C, Pino-Yanes M, Maitland-van der Zee AH; PiCA and SysPharmPedia consortia. Hernandez-Pacheco N, et al. Eur Respir J. 2021 May 13;57(5):2003388. doi: 10.1183/13993003.03388-2020. Print 2021 May. Eur Respir J. 2021. PMID: 33303529 Free PMC article.
Genome-wide association studies of exacerbations in children using long-acting beta2-agonists.
Slob EMA, Richards LB, Vijverberg SJH, Longo C, Koppelman GH, Pijnenburg MWH, Bel EHD, Neerincx AH, Herrera Luis E, Perez-Garcia J, Tim Chew F, Yie Sio Y, Andiappan AK, Turner SW, Mukhopadhyay S, Palmer CNA, Hawcutt D, Jorgensen AL, Burchard EG, Hernandez-Pacheco N, Pino-Yanes M, Maitland-van der Zee AH. Slob EMA, et al. Pediatr Allergy Immunol. 2021 Aug;32(6):1197-1207. doi: 10.1111/pai.13494. Epub 2021 Mar 29. Pediatr Allergy Immunol. 2021. PMID: 33706416 Free PMC article.
27 results