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Page 1
Structure-Based Identification and Biological Characterization of New NAPRT Inhibitors.
Franco J, Piacente F, Walter M, Fratta S, Ghanem M, Benzi A, Caffa I, Kurkin AV, Altieri A, Herr P, Martínez-Bailén M, Robina I, Bruzzone S, Nencioni A, Del Rio A. Franco J, et al. Among authors: herr p. Pharmaceuticals (Basel). 2022 Jul 12;15(7):855. doi: 10.3390/ph15070855. Pharmaceuticals (Basel). 2022. PMID: 35890155 Free PMC article.
NUDT22 promotes cancer growth through pyrimidine salvage.
Walter M, Mayr F, Hanna BMF, Cookson V, Mortusewicz O, Helleday T, Herr P. Walter M, et al. Among authors: herr p. Oncogene. 2023 Apr;42(16):1282-1293. doi: 10.1038/s41388-023-02643-4. Epub 2023 Mar 4. Oncogene. 2023. PMID: 36871087 Free PMC article.
Targeting OGG1 arrests cancer cell proliferation by inducing replication stress.
Visnes T, Benítez-Buelga C, Cázares-Körner A, Sanjiv K, Hanna BMF, Mortusewicz O, Rajagopal V, Albers JJ, Hagey DW, Bekkhus T, Eshtad S, Baquero JM, Masuyer G, Wallner O, Müller S, Pham T, Göktürk C, Rasti A, Suman S, Torres-Ruiz R, Sarno A, Wiita E, Homan EJ, Karsten S, Marimuthu K, Michel M, Koolmeister T, Scobie M, Loseva O, Almlöf I, Unterlass JE, Pettke A, Boström J, Pandey M, Gad H, Herr P, Jemth AS, El Andaloussi S, Kalderén C, Rodriguez-Perales S, Benítez J, Krokan HE, Altun M, Stenmark P, Berglund UW, Helleday T. Visnes T, et al. Among authors: herr p. Nucleic Acids Res. 2020 Dec 2;48(21):12234-12251. doi: 10.1093/nar/gkaa1048. Nucleic Acids Res. 2020. PMID: 33211885 Free PMC article.
Validation and development of MTH1 inhibitors for treatment of cancer.
Warpman Berglund U, Sanjiv K, Gad H, Kalderén C, Koolmeister T, Pham T, Gokturk C, Jafari R, Maddalo G, Seashore-Ludlow B, Chernobrovkin A, Manoilov A, Pateras IS, Rasti A, Jemth AS, Almlöf I, Loseva O, Visnes T, Einarsdottir BO, Gaugaz FZ, Saleh A, Platzack B, Wallner OA, Vallin KS, Henriksson M, Wakchaure P, Borhade S, Herr P, Kallberg Y, Baranczewski P, Homan EJ, Wiita E, Nagpal V, Meijer T, Schipper N, Rudd SG, Bräutigam L, Lindqvist A, Filppula A, Lee TC, Artursson P, Nilsson JA, Gorgoulis VG, Lehtiö J, Zubarev RA, Scobie M, Helleday T. Warpman Berglund U, et al. Among authors: herr p. Ann Oncol. 2016 Dec;27(12):2275-2283. doi: 10.1093/annonc/mdw429. Epub 2016 Nov 8. Ann Oncol. 2016. PMID: 27827301 Free article.
[No title available]
[No authors listed] [No authors listed] PMID: 33451697
NUDT15 Hydrolyzes 6-Thio-DeoxyGTP to Mediate the Anticancer Efficacy of 6-Thioguanine.
Valerie NC, Hagenkort A, Page BD, Masuyer G, Rehling D, Carter M, Bevc L, Herr P, Homan E, Sheppard NG, Stenmark P, Jemth AS, Helleday T. Valerie NC, et al. Among authors: herr p. Cancer Res. 2016 Sep 15;76(18):5501-11. doi: 10.1158/0008-5472.CAN-16-0584. Epub 2016 Aug 16. Cancer Res. 2016. PMID: 27530327 Free PMC article.
63 results