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Targeting cancer stem cell OXPHOS with tailored ruthenium complexes as a new anti-cancer strategy.
Alcalá S, Villarino L, Ruiz-Cañas L, Couceiro JR, Martínez-Calvo M, Palencia-Campos A, Navarro D, Cabezas-Sainz P, Rodriguez-Arabaolaza I, Cordero-Barreal A, Trilla-Fuertes L, Rubiolo JA, Batres-Ramos S, Vallespinos M, González-Páramos C, Rodríguez J, Gámez-Pozo A, Vara JÁF, Fernández SF, Berlinches AB, Moreno-Mata N, Redondo AMT, Carrato A, Hermann PC, Sánchez L, Torrente S, Fernández-Moreno MÁ, Mascareñas JL, Sainz B Jr. Alcalá S, et al. Among authors: hermann pc. J Exp Clin Cancer Res. 2024 Jan 27;43(1):33. doi: 10.1186/s13046-023-02931-7. J Exp Clin Cancer Res. 2024. PMID: 38281027 Free PMC article.
Nodal/Activin signaling drives self-renewal and tumorigenicity of pancreatic cancer stem cells and provides a target for combined drug therapy.
Lonardo E, Hermann PC, Mueller MT, Huber S, Balic A, Miranda-Lorenzo I, Zagorac S, Alcala S, Rodriguez-Arabaolaza I, Ramirez JC, Torres-Ruíz R, Garcia E, Hidalgo M, Cebrián DÁ, Heuchel R, Löhr M, Berger F, Bartenstein P, Aicher A, Heeschen C. Lonardo E, et al. Among authors: hermann pc. Cell Stem Cell. 2011 Nov 4;9(5):433-46. doi: 10.1016/j.stem.2011.10.001. Cell Stem Cell. 2011. PMID: 22056140 Free article.
Vascular incorporation of endothelial colony-forming cells is essential for functional recovery of murine ischemic tissue following cell therapy.
Schwarz TM, Leicht SF, Radic T, Rodriguez-Arabaolaza I, Hermann PC, Berger F, Saif J, Böcker W, Ellwart JW, Aicher A, Heeschen C. Schwarz TM, et al. Among authors: hermann pc. Arterioscler Thromb Vasc Biol. 2012 Feb;32(2):e13-21. doi: 10.1161/ATVBAHA.111.239822. Epub 2011 Dec 22. Arterioscler Thromb Vasc Biol. 2012. PMID: 22199368
Metastatic cancer stem cells--quo vadis?
Hermann PC, Heeschen C. Hermann PC, et al. Clin Chem. 2013 Aug;59(8):1268-9. doi: 10.1373/clinchem.2012.197830. Epub 2013 Jan 3. Clin Chem. 2013. PMID: 23288488 No abstract available.
Nicotine promotes initiation and progression of KRAS-induced pancreatic cancer via Gata6-dependent dedifferentiation of acinar cells in mice.
Hermann PC, Sancho P, Cañamero M, Martinelli P, Madriles F, Michl P, Gress T, de Pascual R, Gandia L, Guerra C, Barbacid M, Wagner M, Vieira CR, Aicher A, Real FX, Sainz B Jr, Heeschen C. Hermann PC, et al. Gastroenterology. 2014 Nov;147(5):1119-33.e4. doi: 10.1053/j.gastro.2014.08.002. Epub 2014 Aug 12. Gastroenterology. 2014. PMID: 25127677
Microenvironmental hCAP-18/LL-37 promotes pancreatic ductal adenocarcinoma by activating its cancer stem cell compartment.
Sainz B Jr, Alcala S, Garcia E, Sanchez-Ripoll Y, Azevedo MM, Cioffi M, Tatari M, Miranda-Lorenzo I, Hidalgo M, Gomez-Lopez G, Cañamero M, Erkan M, Kleeff J, García-Silva S, Sancho P, Hermann PC, Heeschen C. Sainz B Jr, et al. Among authors: hermann pc. Gut. 2015 Dec;64(12):1921-35. doi: 10.1136/gutjnl-2014-308935. Epub 2015 Apr 3. Gut. 2015. PMID: 25841238
The ever-changing landscape of pancreatic cancer stem cells.
Sancho P, Alcala S, Usachov V, Hermann PC, Sainz B Jr. Sancho P, et al. Among authors: hermann pc. Pancreatology. 2016 Jul-Aug;16(4):489-96. doi: 10.1016/j.pan.2016.04.004. Epub 2016 Apr 14. Pancreatology. 2016. PMID: 27161173 Review.
Human pluripotent stem cell-derived acinar/ductal organoids generate human pancreas upon orthotopic transplantation and allow disease modelling.
Hohwieler M, Illing A, Hermann PC, Mayer T, Stockmann M, Perkhofer L, Eiseler T, Antony JS, Müller M, Renz S, Kuo CC, Lin Q, Sendler M, Breunig M, Kleiderman SM, Lechel A, Zenker M, Leichsenring M, Rosendahl J, Zenke M, Sainz B Jr, Mayerle J, Costa IG, Seufferlein T, Kormann M, Wagner M, Liebau S, Kleger A. Hohwieler M, et al. Among authors: hermann pc. Gut. 2017 Mar;66(3):473-486. doi: 10.1136/gutjnl-2016-312423. Epub 2016 Sep 15. Gut. 2017. PMID: 27633923 Free PMC article.
Pancreatic cancer stem cells: A state or an entity?
Hermann PC, Sainz B Jr. Hermann PC, et al. Semin Cancer Biol. 2018 Dec;53:223-231. doi: 10.1016/j.semcancer.2018.08.007. Epub 2018 Aug 18. Semin Cancer Biol. 2018. PMID: 30130664 Free article. Review.
51 results