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Long-term expanding human airway organoids for disease modeling.
Sachs N, Papaspyropoulos A, Zomer-van Ommen DD, Heo I, Böttinger L, Klay D, Weeber F, Huelsz-Prince G, Iakobachvili N, Amatngalim GD, de Ligt J, van Hoeck A, Proost N, Viveen MC, Lyubimova A, Teeven L, Derakhshan S, Korving J, Begthel H, Dekkers JF, Kumawat K, Ramos E, van Oosterhout MF, Offerhaus GJ, Wiener DJ, Olimpio EP, Dijkstra KK, Smit EF, van der Linden M, Jaksani S, van de Ven M, Jonkers J, Rios AC, Voest EE, van Moorsel CH, van der Ent CK, Cuppen E, van Oudenaarden A, Coenjaerts FE, Meyaard L, Bont LJ, Peters PJ, Tans SJ, van Zon JS, Boj SF, Vries RG, Beekman JM, Clevers H. Sachs N, et al. Among authors: heo i. EMBO J. 2019 Feb 15;38(4):e100300. doi: 10.15252/embj.2018100300. Epub 2019 Jan 14. EMBO J. 2019. PMID: 30643021 Free PMC article.
Disease Modeling in Stem Cell-Derived 3D Organoid Systems.
Dutta D, Heo I, Clevers H. Dutta D, et al. Among authors: heo i. Trends Mol Med. 2017 May;23(5):393-410. doi: 10.1016/j.molmed.2017.02.007. Epub 2017 Mar 21. Trends Mol Med. 2017. PMID: 28341301 Review.
Expanding intestinal stem cells in culture.
Heo I, Clevers H. Heo I, et al. Cell Res. 2015 Sep;25(9):995-6. doi: 10.1038/cr.2015.83. Epub 2015 Jul 14. Cell Res. 2015. PMID: 26169607 Free PMC article.
Modelling Cryptosporidium infection in human small intestinal and lung organoids.
Heo I, Dutta D, Schaefer DA, Iakobachvili N, Artegiani B, Sachs N, Boonekamp KE, Bowden G, Hendrickx APA, Willems RJL, Peters PJ, Riggs MW, O'Connor R, Clevers H. Heo I, et al. Nat Microbiol. 2018 Jul;3(7):814-823. doi: 10.1038/s41564-018-0177-8. Epub 2018 Jun 25. Nat Microbiol. 2018. PMID: 29946163 Free PMC article.
Probing the Tumor Suppressor Function of BAP1 in CRISPR-Engineered Human Liver Organoids.
Artegiani B, van Voorthuijsen L, Lindeboom RGH, Seinstra D, Heo I, Tapia P, López-Iglesias C, Postrach D, Dayton T, Oka R, Hu H, van Boxtel R, van Es JH, Offerhaus J, Peters PJ, van Rheenen J, Vermeulen M, Clevers H. Artegiani B, et al. Among authors: heo i. Cell Stem Cell. 2019 Jun 6;24(6):927-943.e6. doi: 10.1016/j.stem.2019.04.017. Epub 2019 May 23. Cell Stem Cell. 2019. PMID: 31130514 Free article.
Intestinal organoid cocultures with microbes.
Puschhof J, Pleguezuelos-Manzano C, Martinez-Silgado A, Akkerman N, Saftien A, Boot C, de Waal A, Beumer J, Dutta D, Heo I, Clevers H. Puschhof J, et al. Among authors: heo i. Nat Protoc. 2021 Oct;16(10):4633-4649. doi: 10.1038/s41596-021-00589-z. Epub 2021 Aug 11. Nat Protoc. 2021. PMID: 34381208 Review.
105 results