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Hypoalbuminemia affects the spatio-temporal tissue distribution of ochratoxin A in liver and kidneys: consequences for organ toxicity.
Hassan R, Friebel A, Brackhagen L, Hobloss Z, Myllys M, González D, Albrecht W, Mohammed ESI, Seddek AL, Marchan R, Cadenas C, Cramer B, Humpf HU, Hartl L, Simbrunner B, Reiberger T, Trauner M, Hoehme S, Degen GH, Hengstler JG, Ghallab A. Hassan R, et al. Among authors: hengstler jg. Arch Toxicol. 2022 Nov;96(11):2967-2981. doi: 10.1007/s00204-022-03361-8. Epub 2022 Aug 13. Arch Toxicol. 2022. PMID: 35962801 Free PMC article.
Inhibition of cytochrome P450 enhances the nephro- and hepatotoxicity of ochratoxin A.
Hassan R, González D, Hobloss Z, Brackhagen L, Myllys M, Friebel A, Seddek AL, Marchan R, Cramer B, Humpf HU, Hoehme S, Degen GH, Hengstler JG, Ghallab A. Hassan R, et al. Among authors: hengstler jg. Arch Toxicol. 2022 Dec;96(12):3349-3361. doi: 10.1007/s00204-022-03395-y. Epub 2022 Oct 13. Arch Toxicol. 2022. PMID: 36227364 Free PMC article.
Protocols for staining of bile canalicular and sinusoidal networks of human, mouse and pig livers, three-dimensional reconstruction and quantification of tissue microarchitecture by image processing and analysis.
Hammad S, Hoehme S, Friebel A, von Recklinghausen I, Othman A, Begher-Tibbe B, Reif R, Godoy P, Johann T, Vartak A, Golka K, Bucur PO, Vibert E, Marchan R, Christ B, Dooley S, Meyer C, Ilkavets I, Dahmen U, Dirsch O, Böttger J, Gebhardt R, Drasdo D, Hengstler JG. Hammad S, et al. Among authors: hengstler jg. Arch Toxicol. 2014 May;88(5):1161-83. doi: 10.1007/s00204-014-1243-5. Epub 2014 Apr 19. Arch Toxicol. 2014. PMID: 24748404 Free PMC article.
The transcription factor CHOP, a central component of the transcriptional regulatory network induced upon CCl4 intoxication in mouse liver, is not a critical mediator of hepatotoxicity.
Campos G, Schmidt-Heck W, Ghallab A, Rochlitz K, Pütter L, Medinas DB, Hetz C, Widera A, Cadenas C, Begher-Tibbe B, Reif R, Günther G, Sachinidis A, Hengstler JG, Godoy P. Campos G, et al. Among authors: hengstler jg. Arch Toxicol. 2014 Jun;88(6):1267-80. doi: 10.1007/s00204-014-1240-8. Epub 2014 Apr 20. Arch Toxicol. 2014. PMID: 24748426
Gene network activity in cultivated primary hepatocytes is highly similar to diseased mammalian liver tissue.
Godoy P, Widera A, Schmidt-Heck W, Campos G, Meyer C, Cadenas C, Reif R, Stöber R, Hammad S, Pütter L, Gianmoena K, Marchan R, Ghallab A, Edlund K, Nüssler A, Thasler WE, Damm G, Seehofer D, Weiss TS, Dirsch O, Dahmen U, Gebhardt R, Chaudhari U, Meganathan K, Sachinidis A, Kelm J, Hofmann U, Zahedi RP, Guthke R, Blüthgen N, Dooley S, Hengstler JG. Godoy P, et al. Among authors: hengstler jg. Arch Toxicol. 2016 Oct;90(10):2513-29. doi: 10.1007/s00204-016-1761-4. Epub 2016 Jun 23. Arch Toxicol. 2016. PMID: 27339419 Free PMC article.
549 results