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Antigen-specific active immunotherapy for ovarian cancer.
Leffers N, Daemen T, Helfrich W, Boezen HM, Cohlen BJ, Melief K, Nijman HW. Leffers N, et al. Among authors: helfrich w. Cochrane Database Syst Rev. 2010 Jan 20;(1):CD007287. doi: 10.1002/14651858.CD007287.pub2. Cochrane Database Syst Rev. 2010. PMID: 20091627 Updated. Review.
Galectin-9 activates and expands human T-helper 1 cells.
Gooden MJ, Wiersma VR, Samplonius DF, Gerssen J, van Ginkel RJ, Nijman HW, Hirashima M, Niki T, Eggleton P, Helfrich W, Bremer E. Gooden MJ, et al. Among authors: helfrich w. PLoS One. 2013 May 31;8(5):e65616. doi: 10.1371/journal.pone.0065616. Print 2013. PLoS One. 2013. PMID: 23741502 Free PMC article.
Antigen-specific active immunotherapy for ovarian cancer.
Leffers N, Daemen T, Helfrich W, Boezen HM, Cohlen BJ, Melief CJ, Nijman HW. Leffers N, et al. Among authors: helfrich w. Cochrane Database Syst Rev. 2014 Sep 17;(9):CD007287. doi: 10.1002/14651858.CD007287.pub3. Cochrane Database Syst Rev. 2014. PMID: 25229990 Updated. Review.
The epithelial polarity regulator LGALS9/galectin-9 induces fatal frustrated autophagy in KRAS mutant colon carcinoma that depends on elevated basal autophagic flux.
Wiersma VR, de Bruyn M, Wei Y, van Ginkel RJ, Hirashima M, Niki T, Nishi N, Zhou J, Pouwels SD, Samplonius DF, Nijman HW, Eggleton P, Helfrich W, Bremer E. Wiersma VR, et al. Among authors: helfrich w. Autophagy. 2015;11(8):1373-88. doi: 10.1080/15548627.2015.1063767. Autophagy. 2015. PMID: 26086204 Free PMC article.
CD103+ intraepithelial T cells in high-grade serous ovarian cancer are phenotypically diverse TCRαβ+ CD8αβ+ T cells that can be targeted for cancer immunotherapy.
Komdeur FL, Wouters MC, Workel HH, Tijans AM, Terwindt AL, Brunekreeft KL, Plat A, Klip HG, Eggink FA, Leffers N, Helfrich W, Samplonius DF, Bremer E, Wisman GB, Daemen T, Duiker EW, Hollema H, Nijman HW, de Bruyn M. Komdeur FL, et al. Among authors: helfrich w. Oncotarget. 2016 Nov 15;7(46):75130-75144. doi: 10.18632/oncotarget.12077. Oncotarget. 2016. PMID: 27650547 Free PMC article.
143 results