Held W - Search Results

1

Graft-versus-host disease is locally maintained in target tissues by resident progenitor-like T cells.

Sacirbegovic F, Günther M, Greco A, Zhao D, Wang X, Zhou M, Rosenberger S, Oberbarnscheidt MH, Held W, McNiff J, Jain D, Höfer T, Shlomchik WD. Sacirbegovic F, et al. Among authors: held w. Immunity. 2023 Feb 14;56(2):369-385.e6. doi: 10.1016/j.immuni.2023.01.003. Epub 2023 Jan 30. Immunity. 2023. PMID: 36720219 Free PMC article.

2

The alarmin interleukin-33 promotes the expansion and preserves the stemness of Tcf-1⁺ CD8⁺ T cells in chronic viral infection.

Marx AF, Kallert SM, Brunner TM, Villegas JA, Geier F, Fixemer J, Abreu-Mota T, Reuther P, Bonilla WV, Fadejeva J, Kreutzfeldt M, Wagner I, Aparicio-Domingo P, Scarpellino L, Charmoy M, Utzschneider DT, Hagedorn C, Lu M, Cornille K, Stauffer K, Kreppel F, Merkler D, Zehn D, Held W, Luther SA, Löhning M, Pinschewer DD. Marx AF, et al. Among authors: held w. Immunity. 2023 Apr 11;56(4):813-828.e10. doi: 10.1016/j.immuni.2023.01.029. Epub 2023 Feb 20. Immunity. 2023. PMID: 36809763 Free article.

3

Hugh Robson MacDonald (1946-2023).

Wilson A, Ferrero I, Speiser DE, Held W, Romero P. Wilson A, et al. Among authors: held w. Immunity. 2023 May 9;56(5):893-894. doi: 10.1016/j.immuni.2023.04.018. Immunity. 2023. PMID: 37163986 No abstract available.

4

Induction of mitochondrial recycling reverts age-associated decline of the hematopoietic and immune systems.

Girotra M, Chiang YH, Charmoy M, Ginefra P, Hope HC, Bataclan C, Yu YR, Schyrr F, Franco F, Geiger H, Cherix S, Ho PC, Naveiras O, Auwerx J, Held W, Vannini N. Girotra M, et al. Among authors: held w. Nat Aging. 2023 Sep;3(9):1057-1066. doi: 10.1038/s43587-023-00473-3. Epub 2023 Aug 31. Nat Aging. 2023. PMID: 37653255

5

Emergence and fate of stem cell-like Tcf7⁺ CD8⁺ T cells during a primary immune response to viral infection.

Silva JG, Pais Ferreira D, Dumez A, Wyss T, Veber R, Danilo M, Pinschewer DD, Charmoy M, Held W. Silva JG, et al. Among authors: held w. Sci Immunol. 2023 Nov 17;8(89):eadh3113. doi: 10.1126/sciimmunol.adh3113. Epub 2023 Nov 17. Sci Immunol. 2023. PMID: 37976346

6

Activation of the transcription factor NFAT5 in the tumor microenvironment enforces CD8⁺ T cell exhaustion.

Tillé L, Cropp D, Charmoy M, Reichenbach P, Andreatta M, Wyss T, Bodley G, Crespo I, Nassiri S, Lourenco J, Leblond MM, Lopez-Rodriguez C, Speiser DE, Coukos G, Irving M, Carmona SJ, Held W, Verdeil G. Tillé L, et al. Among authors: held w. Nat Immunol. 2023 Oct;24(10):1645-1653. doi: 10.1038/s41590-023-01614-x. Epub 2023 Sep 14. Nat Immunol. 2023. PMID: 37709986

7

Stem-cell-like T cells have a specific entry gate to the tumor.

Held W, Luther SA, Petrova TV. Held W, et al. Cancer Cell. 2022 Mar 14;40(3):243-245. doi: 10.1016/j.ccell.2022.02.004. Epub 2022 Feb 16. Cancer Cell. 2022. PMID: 35176235 Free article.

8

PD-1⁺ Tcf1⁺ CD8⁺ T cells from established chronic infection can form memory while retaining a stable imprint of persistent antigen exposure.

Charmoy M, Wyss T, Delorenzi M, Held W. Charmoy M, et al. Among authors: held w. Cell Rep. 2021 Nov 9;37(6):110010. doi: 10.1016/j.celrep.2021.110010. Cell Rep. 2021. PMID: 34758296 Free article. No abstract available.

9

PD-1⁺ Tcf1⁺ CD8⁺ T cells from established chronic infection can form memory while retaining a stableimprint of persistent antigen exposure.

Charmoy M, Wyss T, Delorenzi M, Held W. Charmoy M, et al. Among authors: held w. Cell Rep. 2021 Sep 7;36(10):109672. doi: 10.1016/j.celrep.2021.109672. Cell Rep. 2021. PMID: 34496259 Free article.

10

Metabolic reprogramming of terminally exhausted CD8⁺ T cells by IL-10 enhances anti-tumor immunity.

Guo Y, Xie YQ, Gao M, Zhao Y, Franco F, Wenes M, Siddiqui I, Bevilacqua A, Wang H, Yang H, Feng B, Xie X, Sabatel CM, Tschumi B, Chaiboonchoe A, Wang Y, Li W, Xiao W, Held W, Romero P, Ho PC, Tang L. Guo Y, et al. Among authors: held w. Nat Immunol. 2021 Jun;22(6):746-756. doi: 10.1038/s41590-021-00940-2. Epub 2021 May 24. Nat Immunol. 2021. PMID: 34031618 Free PMC article.

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