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Nucleocapsid-specific T cell responses associate with control of SARS-CoV-2 in the upper airways before seroconversion.
Eser TM, Baranov O, Huth M, Ahmed MIM, Deák F, Held K, Lin L, Pekayvaz K, Leunig A, Nicolai L, Pollakis G, Buggert M, Price DA, Rubio-Acero R, Reich J, Falk P, Markgraf A, Puchinger K, Castelletti N, Olbrich L, Vanshylla K, Klein F, Wieser A, Hasenauer J, Kroidl I, Hoelscher M, Geldmacher C. Eser TM, et al. Among authors: held k. Nat Commun. 2023 May 24;14(1):2952. doi: 10.1038/s41467-023-38020-8. Nat Commun. 2023. PMID: 37225706 Free PMC article.
Phenotypic Changes on Mycobacterium Tuberculosis-Specific CD4 T Cells as Surrogate Markers for Tuberculosis Treatment Efficacy.
Ahmed MIM, Ntinginya NE, Kibiki G, Mtafya BA, Semvua H, Mpagama S, Mtabho C, Saathoff E, Held K, Loose R, Kroidl I, Chachage M, von Both U, Haule A, Mekota AM, Boeree MJ, Gillespie SH, Hoelscher M, Heinrich N, Geldmacher C. Ahmed MIM, et al. Among authors: held k. Front Immunol. 2018 Sep 28;9:2247. doi: 10.3389/fimmu.2018.02247. eCollection 2018. Front Immunol. 2018. PMID: 30323818 Free PMC article.
Envelope-Specific Recognition Patterns of HIV Vaccine-Induced IgG Antibodies Are Linked to Immunogen Structure and Sequence.
Nadai Y, Held K, Joseph S, Ahmed MIM, Hoffmann VS, Peterhoff D, Missanga M, Bauer A, Joachim A, Reimer U, Zerweck J, McCormack S, Cope AV, Tatoud R, Shattock RJ, Robb ML, Sandstroem EG, Hoelscher M, Maboko L, Bakari M, Kroidl A, Wagner R, Weber J, Pollakis G, Geldmacher C. Nadai Y, et al. Among authors: held k. Front Immunol. 2019 Apr 24;10:717. doi: 10.3389/fimmu.2019.00717. eCollection 2019. Front Immunol. 2019. PMID: 31105688 Free PMC article.
Induction of Identical IgG HIV-1 Envelope Epitope Recognition Patterns After Initial HIVIS-DNA/MVA-CMDR Immunization and a Late MVA-CMDR Boost.
Joachim A, Ahmed MIM, Pollakis G, Rogers L, Hoffmann VS, Munseri P, Aboud S, Lyamuya EF, Bakari M, Robb ML, Wahren B, Sandstrom E, Nilsson C, Biberfeld G, Geldmacher C, Held K. Joachim A, et al. Among authors: held k. Front Immunol. 2020 Apr 28;11:719. doi: 10.3389/fimmu.2020.00719. eCollection 2020. Front Immunol. 2020. PMID: 32411138 Free PMC article. Clinical Trial.
Depletion and activation of mucosal CD4 T cells in HIV infected women with HPV-associated lesions of the cervix uteri.
Mbuya W, Mcharo R, Mhizde J, Mnkai J, Mahenge A, Mwakatima M, Mwalongo W, Chiwerengo N, Hölscher M, Lennemann T, Saathoff E, Rwegoshora F, Torres L, Kroidl A, Geldmacher C, Held K, Chachage M. Mbuya W, et al. Among authors: held k. PLoS One. 2020 Oct 2;15(10):e0240154. doi: 10.1371/journal.pone.0240154. eCollection 2020. PLoS One. 2020. PMID: 33007050 Free PMC article.
HIV DNA reservoir and elevated PD-1 expression of CD4 T-cell subsets particularly persist in the terminal ileum of HIV-positive patients despite cART.
Horn C, Augustin M, Ercanoglu MS, Heger E, Knops E, Bondet V, Duffy D, Chon SH, Nierhoff D, Oette M, Schäfer H, Vivaldi C, Held K, Anderson J, Geldmacher C, Suárez I, Rybniker J, Klein F, Fätkenheuer G, Müller-Trutwin M, Lehmann C. Horn C, et al. Among authors: held k. HIV Med. 2021 May;22(5):397-408. doi: 10.1111/hiv.13031. Epub 2021 Jan 9. HIV Med. 2021. PMID: 33421299 Free article.
CD34T+ Humanized Mouse Model to Study Mucosal HIV-1 Transmission and Prevention.
Vanshylla K, Held K, Eser TM, Gruell H, Kleipass F, Stumpf R, Jain K, Weiland D, Münch J, Grüttner B, Geldmacher C, Klein F. Vanshylla K, et al. Among authors: held k. Vaccines (Basel). 2021 Feb 27;9(3):198. doi: 10.3390/vaccines9030198. Vaccines (Basel). 2021. PMID: 33673566 Free PMC article.
Stepwise Conformational Stabilization of a HIV-1 Clade C Consensus Envelope Trimer Immunogen Impacts the Profile of Vaccine-Induced Antibody Responses.
Hauser A, Carnell G, Held K, Sulbaran G, Tischbierek N, Rogers L, Pollakis G, Tonks P, Hoelscher M, Ding S, Sanders RW, Geldmacher C, Sattentau Q, Weissenhorn W, Heeney JL, Peterhoff D, Wagner R. Hauser A, et al. Among authors: held k. Vaccines (Basel). 2021 Jul 6;9(7):750. doi: 10.3390/vaccines9070750. Vaccines (Basel). 2021. PMID: 34358165 Free PMC article.
Depletion of Human Papilloma Virus E6- and E7-Oncoprotein-Specific T-Cell Responses in Women Living With HIV.
Mbuya W, Held K, Mcharo RD, Haule A, Mhizde J, Mnkai J, Mahenge A, Mwakatima M, Sembo M, Mwalongo W, Agrea P, Hoelscher M, Maboko L, Saathoff E, Geisenberger O, Rwegoshora F, Torres L, Koup RA, Kroidl A, Chachage M, Geldmacher C. Mbuya W, et al. Among authors: held k. Front Immunol. 2021 Oct 25;12:742861. doi: 10.3389/fimmu.2021.742861. eCollection 2021. Front Immunol. 2021. PMID: 34759925 Free PMC article.
440 results