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Primaquine homodimers as potential antiplasmodial and anticancer agents.
Pavić K, Rubinić B, Rajić Z, Fontinha D, Prudêncio M, Uzelac L, Kralj M, Held J, Zorc B. Pavić K, et al. Among authors: held j. Bioorg Med Chem Lett. 2019 Oct 1;29(19):126614. doi: 10.1016/j.bmcl.2019.08.018. Epub 2019 Aug 10. Bioorg Med Chem Lett. 2019. PMID: 31431364
Synthesis and study of cytotoxic activity of 1,2,4-trioxane- and egonol-derived hybrid molecules against Plasmodium falciparum and multidrug-resistant human leukemia cells.
Reiter C, Capcı Karagöz A, Fröhlich T, Klein V, Zeino M, Viertel K, Held J, Mordmüller B, Emirdağ Öztürk S, Anıl H, Efferth T, Tsogoeva SB. Reiter C, et al. Among authors: held j. Eur J Med Chem. 2014 Mar 21;75:403-12. doi: 10.1016/j.ejmech.2014.01.043. Epub 2014 Jan 31. Eur J Med Chem. 2014. PMID: 24561670
3-Hydroxy-N'-arylidenepropanehydrazonamides with Halo-Substituted Phenanthrene Scaffolds Cure P. berghei Infected Mice When Administered Perorally.
Leven M, Knaab TC, Held J, Duffy S, Meister S, Fischli C, Meitzner D, Lehmann U, Lungerich B, Kuna K, Stahlke P, Delves MJ, Buchholz M, Winzeler EA, Avery VM, Mordmüller B, Wittlin S, Kurz T. Leven M, et al. Among authors: held j. J Med Chem. 2017 Jul 27;60(14):6036-6044. doi: 10.1021/acs.jmedchem.7b00140. Epub 2017 Jul 17. J Med Chem. 2017. PMID: 28653845
One-pot, multi-component synthesis and structure-activity relationships of peptoid-based histone deacetylase (HDAC) inhibitors targeting malaria parasites.
Diedrich D, Stenzel K, Hesping E, Antonova-Koch Y, Gebru T, Duffy S, Fisher G, Schöler A, Meister S, Kurz T, Avery VM, Winzeler EA, Held J, Andrews KT, Hansen FK. Diedrich D, et al. Among authors: held j. Eur J Med Chem. 2018 Oct 5;158:801-813. doi: 10.1016/j.ejmech.2018.09.018. Epub 2018 Sep 7. Eur J Med Chem. 2018. PMID: 30245402 Free PMC article.
Novel reverse thia-analogs of fosmidomycin: Synthesis and antiplasmodial activity.
Lienau C, Gräwert T, Alves Avelar LA, Illarionov B, Held J, Knaab TC, Lungerich B, van Geelen L, Meier D, Geissler S, Cynis H, Riederer U, Buchholz M, Kalscheuer R, Bacher A, Mordmüller B, Fischer M, Kurz T. Lienau C, et al. Among authors: held j. Eur J Med Chem. 2019 Nov 1;181:111555. doi: 10.1016/j.ejmech.2019.07.058. Epub 2019 Jul 22. Eur J Med Chem. 2019. PMID: 31382119
Harmicines - harmine and cinnamic acid hybrids as novel antiplasmodial hits.
Perković I, Raić-Malić S, Fontinha D, Prudêncio M, Pessanha de Carvalho L, Held J, Tandarić T, Vianello R, Zorc B, Rajić Z. Perković I, et al. Among authors: held j. Eur J Med Chem. 2020 Feb 1;187:111927. doi: 10.1016/j.ejmech.2019.111927. Epub 2019 Nov 29. Eur J Med Chem. 2020. PMID: 31812035
624 results