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DSM265 for Plasmodium falciparum chemoprophylaxis: a randomised, double blinded, phase 1 trial with controlled human malaria infection.
Sulyok M, Rückle T, Roth A, Mürbeth RE, Chalon S, Kerr N, Samec SS, Gobeau N, Calle CL, Ibáñez J, Sulyok Z, Held J, Gebru T, Granados P, Brückner S, Nguetse C, Mengue J, Lalremruata A, Sim BKL, Hoffman SL, Möhrle JJ, Kremsner PG, Mordmüller B. Sulyok M, et al. Among authors: held j. Lancet Infect Dis. 2017 Jun;17(6):636-644. doi: 10.1016/S1473-3099(17)30139-1. Epub 2017 Mar 28. Lancet Infect Dis. 2017. PMID: 28363637 Free PMC article. Clinical Trial.
Induction of Plasmodium falciparum-specific CD4+ T cells and memory B cells in Gabonese children vaccinated with RTS,S/AS01(E) and RTS,S/AS02(D).
Agnandji ST, Fendel R, Mestré M, Janssens M, Vekemans J, Held J, Gnansounou F, Haertle S, von Glasenapp I, Oyakhirome S, Mewono L, Moris P, Lievens M, Demoitie MA, Dubois PM, Villafana T, Jongert E, Olivier A, Cohen J, Esen M, Kremsner PG, Lell B, Mordmüller B. Agnandji ST, et al. Among authors: held j. PLoS One. 2011 Apr 11;6(4):e18559. doi: 10.1371/journal.pone.0018559. PLoS One. 2011. PMID: 21494604 Free PMC article. Clinical Trial.
Novel approaches in antimalarial drug discovery.
Held J, Kreidenweiss A, Mordmüller B. Held J, et al. Expert Opin Drug Discov. 2013 Nov;8(11):1325-37. doi: 10.1517/17460441.2013.843522. Epub 2013 Oct 3. Expert Opin Drug Discov. 2013. PMID: 24090219 Review.
Synthesis and study of cytotoxic activity of 1,2,4-trioxane- and egonol-derived hybrid molecules against Plasmodium falciparum and multidrug-resistant human leukemia cells.
Reiter C, Capcı Karagöz A, Fröhlich T, Klein V, Zeino M, Viertel K, Held J, Mordmüller B, Emirdağ Öztürk S, Anıl H, Efferth T, Tsogoeva SB. Reiter C, et al. Among authors: held j. Eur J Med Chem. 2014 Mar 21;75:403-12. doi: 10.1016/j.ejmech.2014.01.043. Epub 2014 Jan 31. Eur J Med Chem. 2014. PMID: 24561670
624 results