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The integrin-linked kinase is required for chemokine-triggered high-affinity conformation of the neutrophil β2-integrin LFA-1.
Margraf A, Germena G, Drexler HCA, Rossaint J, Ludwig N, Prystaj B, Mersmann S, Thomas K, Block H, Gottschlich W, Liu C, Krenn PW, Haller H, Heitplatz B, Meyer Zu Brickwedde M, Moser M, Vestweber D, Zarbock A. Margraf A, et al. Among authors: heitplatz b. Blood. 2020 Nov 5;136(19):2200-2205. doi: 10.1182/blood.2020004948. Blood. 2020. PMID: 32730588 Free article.
Skap2 is required for β2 integrin-mediated neutrophil recruitment and functions.
Boras M, Volmering S, Bokemeyer A, Rossaint J, Block H, Bardel B, Van Marck V, Heitplatz B, Kliche S, Reinhold A, Lowell C, Zarbock A. Boras M, et al. Among authors: heitplatz b. J Exp Med. 2017 Mar 6;214(3):851-874. doi: 10.1084/jem.20160647. Epub 2017 Feb 9. J Exp Med. 2017. PMID: 28183734 Free PMC article.
TrkC Is Essential for Nephron Function and Trans-Activates Igf1R Signaling.
Lepa C, Hoppe S, Stöber A, Skryabin BV, Sievers LK, Heitplatz B, Ciarimboli G, Neugebauer U, Lindenmeyer MT, Cohen CD, Drexler HCA, Boor P, Weide T, Pavenstädt H, George B. Lepa C, et al. Among authors: heitplatz b. J Am Soc Nephrol. 2021 Feb;32(2):357-374. doi: 10.1681/ASN.2020040424. Epub 2020 Dec 30. J Am Soc Nephrol. 2021. PMID: 33380522 Free PMC article.
Nephron-specific knockin of the PIKfyve-binding-deficient Vac14L156R mutant results in albuminuria and mesangial expansion.
Michgehl U, Skryabin BV, Bayraktar S, Vollenbröker B, Ciarimboli G, Heitplatz B, Van Marck V, Gröne HJ, Pavenstädt H, Weide T. Michgehl U, et al. Among authors: heitplatz b. Am J Physiol Renal Physiol. 2018 Nov 1;315(5):F1307-F1319. doi: 10.1152/ajprenal.00191.2018. Epub 2018 Aug 1. Am J Physiol Renal Physiol. 2018. PMID: 30066585 Free article.
Increased soluble fms-like tyrosine kinase 1 after ischemia reperfusion contributes to adverse clinical outcomes following kidney transplantation.
Wewers TM, Mayer AB, Pfleiderer A, Beul K, Schmidt R, Heitplatz B, Van Marck V, Nolte I, Pavenstädt H, Reuter S, Brand M, Di Marco GS. Wewers TM, et al. Among authors: heitplatz b. Kidney Int. 2019 May;95(5):1091-1102. doi: 10.1016/j.kint.2018.11.023. Epub 2019 Feb 26. Kidney Int. 2019. PMID: 30824181 Free article.
Renal Contrast-Enhanced Sonography Findings in a Model of Acute Cellular Allograft Rejection.
Grabner A, Kentrup D, Pawelski H, Mühlmeister M, Biermann C, Edemir B, Heitplatz B, Van Marck V, Bettinger T, Pavenstädt H, Schlatter E, Stypmann J, Tiemann K, Reuter S. Grabner A, et al. Among authors: heitplatz b. Am J Transplant. 2016 May;16(5):1612-9. doi: 10.1111/ajt.13648. Epub 2016 Feb 26. Am J Transplant. 2016. PMID: 26613381 Free article.
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