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Extracellular cyclophilin A activates platelets via EMMPRIN (CD147) and PI3K/Akt signaling, which promotes platelet adhesion and thrombus formation in vitro and in vivo.
Seizer P, Ungern-Sternberg SN, Schönberger T, Borst O, Münzer P, Schmidt EM, Mack AF, Heinzmann D, Chatterjee M, Langer H, Malešević M, Lang F, Gawaz M, Fischer G, May AE. Seizer P, et al. Among authors: heinzmann d. Arterioscler Thromb Vasc Biol. 2015 Mar;35(3):655-63. doi: 10.1161/ATVBAHA.114.305112. Epub 2014 Dec 30. Arterioscler Thromb Vasc Biol. 2015. PMID: 25550208
The Novel Extracellular Cyclophilin A (CyPA) - Inhibitor MM284 Reduces Myocardial Inflammation and Remodeling in a Mouse Model of Troponin I -Induced Myocarditis.
Heinzmann D, Bangert A, Müller AM, von Ungern-Sternberg SN, Emschermann F, Schönberger T, Chatterjee M, Mack AF, Klingel K, Kandolf R, Malesevic M, Borst O, Gawaz M, Langer HF, Katus H, Fischer G, May AE, Kaya Z, Seizer P. Heinzmann D, et al. PLoS One. 2015 Apr 20;10(4):e0124606. doi: 10.1371/journal.pone.0124606. eCollection 2015. PLoS One. 2015. PMID: 25894208 Free PMC article.
Ablation of an electrical storm in a patient with giant cell myocarditis using continuous flow left ventricular assist device and percutaneous right ventricular assist device.
Heinzmann D, Schibilsky D, Gramlich M, Klingel K, Kandolf R, Rosenberger P, Gawaz M, Schreieck J, Schlensak C, Seizer P. Heinzmann D, et al. Int J Cardiol. 2016 Apr 15;209:84-6. doi: 10.1016/j.ijcard.2016.02.060. Epub 2016 Feb 3. Int J Cardiol. 2016. PMID: 26882191 No abstract available.
Comparison of Ventricular Inducibility with Late Gadolinium Enhancement and Myocardial Inflammation in Endomyocardial Biopsy in Patients with Dilated Cardiomyopathy.
Mueller KA, Heck C, Heinzmann D, Schwille J, Klingel K, Kandolf R, Kramer U, Gramlich M, Geisler T, Gawaz MP, Schreieck J, Seizer P. Mueller KA, et al. Among authors: heinzmann d. PLoS One. 2016 Dec 8;11(12):e0167616. doi: 10.1371/journal.pone.0167616. eCollection 2016. PLoS One. 2016. PMID: 27930686 Free PMC article.
Histopathological and Immunological Characteristics of Tachycardia-Induced Cardiomyopathy.
Mueller KAL, Heinzmann D, Klingel K, Fallier-Becker P, Kandolf R, Kilias A, Walker-Allgaier B, Borst O, Kumbrink J, Kirchner T, Langer H, Geisler T, Schreieck J, Gramlich M, Gawaz M, Seizer P. Mueller KAL, et al. Among authors: heinzmann d. J Am Coll Cardiol. 2017 May 2;69(17):2160-2172. doi: 10.1016/j.jacc.2017.02.049. J Am Coll Cardiol. 2017. PMID: 28449778 Free article.
62 results