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Page 1
Antibody targeting of E3 ubiquitin ligases for receptor degradation.
Marei H, Tsai WK, Kee YS, Ruiz K, He J, Cox C, Sun T, Penikalapati S, Dwivedi P, Choi M, Kan D, Saenz-Lopez P, Dorighi K, Zhang P, Kschonsak YT, Kljavin N, Amin D, Kim I, Mancini AG, Nguyen T, Wang C, Janezic E, Doan A, Mai E, Xi H, Gu C, Heinlein M, Biehs B, Wu J, Lehoux I, Harris S, Comps-Agrar L, Seshasayee D, de Sauvage FJ, Grimmer M, Li J, Agard NJ, de Sousa E Melo F. Marei H, et al. Among authors: heinlein m. Nature. 2022 Oct;610(7930):182-189. doi: 10.1038/s41586-022-05235-6. Epub 2022 Sep 21. Nature. 2022. PMID: 36131013 Free PMC article.
Disruption of stem cell niche-confined R-spondin 3 expression leads to impaired hematopoiesis.
Kurtova AV, Heinlein M, Haas S, Velten L, Dijkgraaf GJP, Storm EE, Kljavin NM, Boumahdi S, Himmels P, Herault A, Mancini A, Koeppen H, Dail M, Yan Q, Zhang J, Koch U, Radtke F, Modrusan Z, Metcalfe C, Piskol R, de Sauvage FJ. Kurtova AV, et al. Among authors: heinlein m. Blood Adv. 2023 Feb 28;7(4):491-507. doi: 10.1182/bloodadvances.2022007714. Blood Adv. 2023. PMID: 35914228 Free PMC article.
Linear ubiquitin chain assembly complex coordinates late thymic T-cell differentiation and regulatory T-cell homeostasis.
Teh CE, Lalaoui N, Jain R, Policheni AN, Heinlein M, Alvarez-Diaz S, Sheridan JM, Rieser E, Deuser S, Darding M, Koay HF, Hu Y, Kupresanin F, O'Reilly LA, Godfrey DI, Smyth GK, Bouillet P, Strasser A, Walczak H, Silke J, Gray DH. Teh CE, et al. Among authors: heinlein m. Nat Commun. 2016 Nov 18;7:13353. doi: 10.1038/ncomms13353. Nat Commun. 2016. PMID: 27857075 Free PMC article.
Dual roles for LUBAC signaling in thymic epithelial cell development and survival.
Jain R, Zhao K, Sheridan JM, Heinlein M, Kupresanin F, Abeysekera W, Hall C, Rickard J, Bouillet P, Walczak H, Strasser A, Silke J, Gray DHD. Jain R, et al. Among authors: heinlein m. Cell Death Differ. 2021 Oct;28(10):2946-2956. doi: 10.1038/s41418-021-00850-8. Epub 2021 Aug 11. Cell Death Differ. 2021. PMID: 34381167 Free PMC article.
A critical epithelial survival axis regulated by MCL-1 maintains thymic function in mice.
Jain R, Sheridan JM, Policheni A, Heinlein M, Gandolfo LC, Dewson G, Smyth GK, Sansom SN, Fu NY, Visvader JE, Holländer GA, Strasser A, Gray DHD. Jain R, et al. Among authors: heinlein m. Blood. 2017 Dec 7;130(23):2504-2515. doi: 10.1182/blood-2017-03-771576. Epub 2017 Sep 29. Blood. 2017. PMID: 28972012 Free PMC article.
112 results