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Function and mechanism of the pyrin inflammasome.
Heilig R, Broz P. Heilig R, et al. Eur J Immunol. 2018 Feb;48(2):230-238. doi: 10.1002/eji.201746947. Epub 2017 Dec 6. Eur J Immunol. 2018. PMID: 29148036 Free article. Review.
RIPK1 activates distinct gasdermins in macrophages and neutrophils upon pathogen blockade of innate immune signaling.
Chen KW, Demarco B, Ramos S, Heilig R, Goris M, Grayczyk JP, Assenmacher CA, Radaelli E, Joannas LD, Henao-Mejia J, Tacchini-Cottier F, Brodsky IE, Broz P. Chen KW, et al. Among authors: heilig r. Proc Natl Acad Sci U S A. 2021 Jul 13;118(28):e2101189118. doi: 10.1073/pnas.2101189118. Proc Natl Acad Sci U S A. 2021. PMID: 34260403 Free PMC article.
The Inflammasome Drives GSDMD-Independent Secondary Pyroptosis and IL-1 Release in the Absence of Caspase-1 Protease Activity.
Schneider KS, Groß CJ, Dreier RF, Saller BS, Mishra R, Gorka O, Heilig R, Meunier E, Dick MS, Ćiković T, Sodenkamp J, Médard G, Naumann R, Ruland J, Kuster B, Broz P, Groß O. Schneider KS, et al. Among authors: heilig r. Cell Rep. 2017 Dec 26;21(13):3846-3859. doi: 10.1016/j.celrep.2017.12.018. Cell Rep. 2017. PMID: 29281832 Free PMC article.
147 results