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TAK1 suppresses a NEMO-dependent but NF-kappaB-independent pathway to liver cancer.
Bettermann K, Vucur M, Haybaeck J, Koppe C, Janssen J, Heymann F, Weber A, Weiskirchen R, Liedtke C, Gassler N, Müller M, de Vos R, Wolf MJ, Boege Y, Seleznik GM, Zeller N, Erny D, Fuchs T, Zoller S, Cairo S, Buendia MA, Prinz M, Akira S, Tacke F, Heikenwalder M, Trautwein C, Luedde T. Bettermann K, et al. Among authors: heikenwalder m. Cancer Cell. 2010 May 18;17(5):481-96. doi: 10.1016/j.ccr.2010.03.021. Cancer Cell. 2010. PMID: 20478530 Free article.
Senescence surveillance of pre-malignant hepatocytes limits liver cancer development.
Kang TW, Yevsa T, Woller N, Hoenicke L, Wuestefeld T, Dauch D, Hohmeyer A, Gereke M, Rudalska R, Potapova A, Iken M, Vucur M, Weiss S, Heikenwalder M, Khan S, Gil J, Bruder D, Manns M, Schirmacher P, Tacke F, Ott M, Luedde T, Longerich T, Kubicka S, Zender L. Kang TW, et al. Among authors: heikenwalder m. Nature. 2011 Nov 9;479(7374):547-51. doi: 10.1038/nature10599. Nature. 2011. PMID: 22080947
Lymphotoxin, NF-ĸB, and cancer: the dark side of cytokines.
Bauer J, Namineni S, Reisinger F, Zöller J, Yuan D, Heikenwälder M. Bauer J, et al. Among authors: heikenwalder m. Dig Dis. 2012;30(5):453-68. doi: 10.1159/000341690. Epub 2012 Oct 24. Dig Dis. 2012. PMID: 23108301 Review.
RIP3 inhibits inflammatory hepatocarcinogenesis but promotes cholestasis by controlling caspase-8- and JNK-dependent compensatory cell proliferation.
Vucur M, Reisinger F, Gautheron J, Janssen J, Roderburg C, Cardenas DV, Kreggenwinkel K, Koppe C, Hammerich L, Hakem R, Unger K, Weber A, Gassler N, Luedde M, Frey N, Neumann UP, Tacke F, Trautwein C, Heikenwalder M, Luedde T. Vucur M, et al. Among authors: heikenwalder m. Cell Rep. 2013 Aug 29;4(4):776-90. doi: 10.1016/j.celrep.2013.07.035. Epub 2013 Aug 22. Cell Rep. 2013. PMID: 23972991 Free article.
Specific and nonhepatotoxic degradation of nuclear hepatitis B virus cccDNA.
Lucifora J, Xia Y, Reisinger F, Zhang K, Stadler D, Cheng X, Sprinzl MF, Koppensteiner H, Makowska Z, Volz T, Remouchamps C, Chou WM, Thasler WE, Hüser N, Durantel D, Liang TJ, Münk C, Heim MH, Browning JL, Dejardin E, Dandri M, Schindler M, Heikenwalder M, Protzer U. Lucifora J, et al. Among authors: heikenwalder m. Science. 2014 Mar 14;343(6176):1221-8. doi: 10.1126/science.1243462. Epub 2014 Feb 20. Science. 2014. PMID: 24557838 Free PMC article.
RIP3, a kinase promoting necroptotic cell death, mediates adverse remodelling after myocardial infarction.
Luedde M, Lutz M, Carter N, Sosna J, Jacoby C, Vucur M, Gautheron J, Roderburg C, Borg N, Reisinger F, Hippe HJ, Linkermann A, Wolf MJ, Rose-John S, Lüllmann-Rauch R, Adam D, Flögel U, Heikenwalder M, Luedde T, Frey N. Luedde M, et al. Among authors: heikenwalder m. Cardiovasc Res. 2014 Jul 15;103(2):206-16. doi: 10.1093/cvr/cvu146. Epub 2014 Jun 11. Cardiovasc Res. 2014. PMID: 24920296 Free article.
326 results