Hegedűs T - Search Results

1

Synergistic Inhibitory Effect of Quercetin and Cyanidin-3O-Sophoroside on ABCB1.

Singh K, Patil RB, Patel V, Remenyik J, Hegedűs T, Goda K. Singh K, et al. Among authors: hegedus t. Int J Mol Sci. 2023 Jul 12;24(14):11341. doi: 10.3390/ijms241411341. Int J Mol Sci. 2023. PMID: 37511101 Free PMC article.

2

High-affinity interaction of tyrosine kinase inhibitors with the ABCG2 multidrug transporter.

Ozvegy-Laczka C, Hegedus T, Várady G, Ujhelly O, Schuetz JD, Váradi A, Kéri G, Orfi L, Német K, Sarkadi B. Ozvegy-Laczka C, et al. Among authors: hegedus t. Mol Pharmacol. 2004 Jun;65(6):1485-95. doi: 10.1124/mol.65.6.1485. Mol Pharmacol. 2004. PMID: 15155841

3

Interaction with the 5D3 monoclonal antibody is regulated by intramolecular rearrangements but not by covalent dimer formation of the human ABCG2 multidrug transporter.

Ozvegy-Laczka C, Laczkó R, Hegedus C, Litman T, Várady G, Goda K, Hegedus T, Dokholyan NV, Sorrentino BP, Váradi A, Sarkadi B. Ozvegy-Laczka C, et al. Among authors: hegedus t, hegedus c. J Biol Chem. 2008 Sep 19;283(38):26059-70. doi: 10.1074/jbc.M803230200. Epub 2008 Jul 21. J Biol Chem. 2008. PMID: 18644784 Free PMC article.

4

Lipid regulation of the ABCB1 and ABCG2 multidrug transporters.

Hegedüs C, Telbisz Á, Hegedűs T, Sarkadi B, Özvegy-Laczka C. Hegedüs C, et al. Among authors: hegedus t. Adv Cancer Res. 2015;125:97-137. doi: 10.1016/bs.acr.2014.10.004. Epub 2015 Jan 8. Adv Cancer Res. 2015. PMID: 25640268 Free article. Review.

5

The linker region of breast cancer resistance protein ABCG2 is critical for coupling of ATP-dependent drug transport.

Macalou S, Robey RW, Jabor Gozzi G, Shukla S, Grosjean I, Hegedus T, Ambudkar SV, Bates SE, Di Pietro A. Macalou S, et al. Among authors: hegedus t. Cell Mol Life Sci. 2016 May;73(9):1927-37. doi: 10.1007/s00018-015-2118-5. Epub 2015 Dec 26. Cell Mol Life Sci. 2016. PMID: 26708291 Free PMC article.

6

Jump into a New Fold-A Homology Based Model for the ABCG2/BCRP Multidrug Transporter.

László L, Sarkadi B, Hegedűs T. László L, et al. Among authors: hegedus t. PLoS One. 2016 Oct 14;11(10):e0164426. doi: 10.1371/journal.pone.0164426. eCollection 2016. PLoS One. 2016. PMID: 27741279 Free PMC article.

7

The transport pathway in the ABCG2 protein and its regulation revealed by molecular dynamics simulations.

Nagy T, Tóth Á, Telbisz Á, Sarkadi B, Tordai H, Tordai A, Hegedűs T. Nagy T, et al. Among authors: hegedus t. Cell Mol Life Sci. 2021 Mar;78(5):2329-2339. doi: 10.1007/s00018-020-03651-3. Epub 2020 Sep 26. Cell Mol Life Sci. 2021. PMID: 32979053 Free PMC article.

8

The ABCG2/BCRP transporter and its variants - from structure to pathology.

Sarkadi B, Homolya L, Hegedűs T. Sarkadi B, et al. Among authors: hegedus t. FEBS Lett. 2020 Dec;594(23):4012-4034. doi: 10.1002/1873-3468.13947. Epub 2020 Oct 16. FEBS Lett. 2020. PMID: 33015850 Free article. Review.

9

Comprehensive Collection and Prediction of ABC Transmembrane Protein Structures in the AI Era of Structural Biology.

Tordai H, Suhajda E, Sillitoe I, Nair S, Varadi M, Hegedus T. Tordai H, et al. Among authors: hegedus t. Int J Mol Sci. 2022 Aug 9;23(16):8877. doi: 10.3390/ijms23168877. Int J Mol Sci. 2022. PMID: 36012140 Free PMC article.

10

The Reentry Helix Is Potentially Involved in Cholesterol Sensing of the ABCG1 Transporter Protein.

Hegyi Z, Hegedűs T, Homolya L. Hegyi Z, et al. Among authors: hegedus t. Int J Mol Sci. 2022 Nov 8;23(22):13744. doi: 10.3390/ijms232213744. Int J Mol Sci. 2022. PMID: 36430223 Free PMC article.

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