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90-day nose-only inhalation toxicity study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Sprague-Dawley rats.
Hu SC, Min S, Kang HK, Yang DJ, Basavarajappa M, Lewis SM, Davis KJ, Patton RE, Bryant MS, Sepehr E, Trbojevich R, Pearce MG, Bishop ME, Ding W, Heflich RH, Maisha MP, Felton R, Chemerynski S, Yee SB, Coraggio M, Rosenfeldt H, Yeager RP, Howard PC, Tang Y. Hu SC, et al. Among authors: heflich rh. Food Chem Toxicol. 2022 Feb;160:112780. doi: 10.1016/j.fct.2021.112780. Epub 2021 Dec 26. Food Chem Toxicol. 2022. PMID: 34965465
Evaluation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) mutagenicity using in vitro and in vivo Pig-a assays.
Mittelstaedt RA, Dobrovolsky VN, Revollo JR, Pearce MG, Wang Y, Dad A, McKinzie PB, Rosenfeldt H, Yucesoy B, Yeager R, Hu SC, Tang Y, Min S, Kang HK, Yang DJ, Basavarajappa M, Heflich RH. Mittelstaedt RA, et al. Among authors: heflich rh. Mutat Res Genet Toxicol Environ Mutagen. 2019 Jan;837:65-72. doi: 10.1016/j.mrgentox.2018.10.007. Epub 2018 Oct 29. Mutat Res Genet Toxicol Environ Mutagen. 2019. PMID: 30595212
14-Day Nose-Only Inhalation Toxicity and Haber's Rule Study of NNK in Sprague-Dawley Rats.
Hu SC, Min S, Kang HK, Yang DJ, Lewis SM, Davis KJ, Patton RE, Bryant MS, Sepehr E, Trbojevich R, Pearce MG, Bishop ME, Heflich RH, Maisha MP, Felton R, Chemerynski S, Yee SB, Coraggio M, Rosenfeldt H, Yeager RP, Howard PC, Tang Y. Hu SC, et al. Among authors: heflich rh. Toxicol Sci. 2021 Sep 28;183(2):319-337. doi: 10.1093/toxsci/kfab094. Toxicol Sci. 2021. PMID: 34329464
In vivo genotoxicity of furan in F344 rats at cancer bioassay doses.
Ding W, Petibone DM, Latendresse JR, Pearce MG, Muskhelishvili L, White GA, Chang CW, Mittelstaedt RA, Shaddock JG, McDaniel LP, Doerge DR, Morris SM, Bishop ME, Manjanatha MG, Aidoo A, Heflich RH. Ding W, et al. Among authors: heflich rh. Toxicol Appl Pharmacol. 2012 Jun 1;261(2):164-71. doi: 10.1016/j.taap.2012.03.021. Epub 2012 Apr 5. Toxicol Appl Pharmacol. 2012. PMID: 22507866
249 results