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High Cysteinyl Leukotriene Receptor 1 Expression Correlates with Poor Survival of Uveal Melanoma Patients and Cognate Antagonist Drugs Modulate the Growth, Cancer Secretome, and Metabolism of Uveal Melanoma Cells.
Slater K, Heeran AB, Garcia-Mulero S, Kalirai H, Sanz-Pamplona R, Rahman A, Al-Attar N, Helmi M, O'Connell F, Bosch R, Portela A, Villanueva A, Gallagher WM, Jensen LD, Piulats JM, Coupland SE, O'Sullivan J, Kennedy BN. Slater K, et al. Among authors: heeran ab. Cancers (Basel). 2020 Oct 13;12(10):2950. doi: 10.3390/cancers12102950. Cancers (Basel). 2020. PMID: 33066024 Free PMC article.
Radiation-induced Bystander Effect (RIBE) alters mitochondrial metabolism using a human rectal cancer ex vivo explant model.
Heeran AB, Berrigan HP, Buckley CE, Bottu HM, Prendiville O, Buckley AM, Clarke N, Donlon NE, Nugent TS, Durand M, Dunne C, Larkin JO, Mehigan B, McCormick P, Brennan L, Lynam-Lennon N, O'Sullivan J. Heeran AB, et al. Transl Oncol. 2021 Jan;14(1):100882. doi: 10.1016/j.tranon.2020.100882. Epub 2020 Oct 23. Transl Oncol. 2021. PMID: 33129115 Free PMC article.
The Protein Secretome Is Altered in Rectal Cancer Tissue Compared to Normal Rectal Tissue, and Alterations in the Secretome Induce Enhanced Innate Immune Responses.
Heeran AB, Dunne MR, Morrissey ME, Buckley CE, Clarke N, Cannon A, Donlon NE, Nugent TS, Durand M, Dunne C, Larkin JO, Mehigan B, McCormick P, Lynam-Lennon N, O'Sullivan J. Heeran AB, et al. Cancers (Basel). 2021 Feb 2;13(3):571. doi: 10.3390/cancers13030571. Cancers (Basel). 2021. PMID: 33540635 Free PMC article.
The Prognostic Value of the Lymph Node in Oesophageal Adenocarcinoma; Incorporating Clinicopathological and Immunological Profiling.
Donlon NE, Davern M, Sheppard A, Power R, O'Connell F, Heeran AB, King R, Hayes C, Bhardwaj A, Phelan JJ, Dunne MR, Ravi N, Donohoe CL, O'Sullivan J, Reynolds JV, Lysaght J. Donlon NE, et al. Among authors: heeran ab. Cancers (Basel). 2021 Aug 9;13(16):4005. doi: 10.3390/cancers13164005. Cancers (Basel). 2021. PMID: 34439160 Free PMC article.
Opposing Immune-Metabolic Signature in Visceral Versus Subcutaneous Adipose Tissue in Patients with Adenocarcinoma of the Oesophagus and the Oesophagogastric Junction.
Heeran AB, McCready J, Dunne MR, Donlon NE, Nugent TS, Bhardwaj A, Mitchelson KAJ, Buckley AM, Ravi N, Roche HM, Reynolds JV, Lynam-Lennon N, O'Sullivan J. Heeran AB, et al. Metabolites. 2021 Nov 10;11(11):768. doi: 10.3390/metabo11110768. Metabolites. 2021. PMID: 34822426 Free PMC article.
PD-1 and TIGIT blockade differentially affect tumour cell survival under hypoxia and glucose deprived conditions in oesophageal adenocarcinoma; implications for overcoming resistance to PD-1 blockade in hypoxic tumours.
Davern M, Fitzgerald MC, Buckley CE, Heeran AB, Donlon NE, McGrath J, O' Connell F, Deshpande MR, Hayes C, MacDonald J, Sheppard AD, Reynolds JV, Maher SG, Lynam-Lennon N, Murphy B, Lysaght J. Davern M, et al. Among authors: heeran ab. Transl Oncol. 2022 May;19:101381. doi: 10.1016/j.tranon.2022.101381. Epub 2022 Mar 1. Transl Oncol. 2022. PMID: 35245832 Free PMC article.
Impact of radiotherapy on the immune landscape in oesophageal adenocarcinoma.
Donlon NE, Davern M, O'Connell F, Sheppard A, Heeran A, Bhardwaj A, Butler C, Narayanasamy R, Donohoe C, Phelan JJ, Lynam-Lennon N, Dunne MR, Maher S, O'Sullivan J, Reynolds JV, Lysaght J. Donlon NE, et al. World J Gastroenterol. 2022 Jun 7;28(21):2302-2319. doi: 10.3748/wjg.v28.i21.2302. World J Gastroenterol. 2022. PMID: 35800186 Free PMC article.
Energy Metabolism, Metabolite, and Inflammatory Profiles in Human Ex Vivo Adipose Tissue Are Influenced by Obesity Status, Metabolic Dysfunction, and Treatment Regimes in Patients with Oesophageal Adenocarcinoma.
O'Connell F, Mylod E, Donlon NE, Heeran AB, Butler C, Bhardwaj A, Ramjit S, Durand M, Lambe G, Tansey P, Welartne I, Sheahan KP, Yin X, Donohoe CL, Ravi N, Dunne MR, Brennan L, Reynolds JV, Roche HM, O'Sullivan J. O'Connell F, et al. Among authors: heeran ab. Cancers (Basel). 2023 Mar 9;15(6):1681. doi: 10.3390/cancers15061681. Cancers (Basel). 2023. PMID: 36980567 Free PMC article.
Potential of damage associated molecular patterns in synergising radiation and the immune response in oesophageal cancer.
Donlon NE, Davern M, Sheppard A, O'Connell F, Moran B, Nugent TS, Heeran A, Phelan JJ, Bhardwaj A, Butler C, Ravi N, Donohoe CL, Lynam-Lennon N, Maher S, Reynolds JV, Lysaght J. Donlon NE, et al. World J Gastrointest Oncol. 2023 Aug 15;15(8):1349-1365. doi: 10.4251/wjgo.v15.i8.1349. World J Gastrointest Oncol. 2023. PMID: 37663943 Free PMC article.
13 results