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Increased CD8 T-cell immunity after COVID-19 vaccination in lymphoid malignancy patients lacking adequate humoral response: An immune compensation mechanism?
Boerenkamp LS, Pothast CR, Dijkland RC, van Dijk K, van Gorkom GNY, van Loo IHM, Wieten L, Halkes CJM, Heemskerk MHM, Van Elssen CHMJ. Boerenkamp LS, et al. Among authors: heemskerk mhm. Am J Hematol. 2022 Dec;97(12):E457-E461. doi: 10.1002/ajh.26729. Epub 2022 Sep 24. Am J Hematol. 2022. PMID: 36106926 Free PMC article. No abstract available.
Prolonged activation of nasal immune cell populations and development of tissue-resident SARS-CoV-2-specific CD8+ T cell responses following COVID-19.
Roukens AHE, Pothast CR, König M, Huisman W, Dalebout T, Tak T, Azimi S, Kruize Y, Hagedoorn RS, Zlei M, Staal FJT, de Bie FJ, van Dongen JJM, Arbous SM, Zhang JLH, Verheij M, Prins C, van der Does AM, Hiemstra PS, de Vries JJC, Janse JJ, Roestenberg M, Myeni SK, Kikkert M, Yazdanbakhsh M, Heemskerk MHM, Smits HH, Jochems SP; in collaboration with BEAT-COVID group; in collaboration with COVID-19 LUMC group. Roukens AHE, et al. Among authors: heemskerk mhm. Nat Immunol. 2022 Jan;23(1):23-32. doi: 10.1038/s41590-021-01095-w. Epub 2021 Dec 22. Nat Immunol. 2022. PMID: 34937933
Immune Determinants of Viral Clearance in Hospitalised COVID-19 Patients: Reduced Circulating Naïve CD4+ T Cell Counts Correspond with Delayed Viral Clearance.
Zlei M, Sidorov IA, Joosten SA, Heemskerk MHM, Myeni SK, Pothast CR, de Brouwer CS, Boomaars-van der Zanden AL, van Meijgaarden KE, Morales ST, Wessels E, Janse JJ, Goeman JJ, Cobbaert CM, Kroes ACM, Cannegieter SC, Roestenberg M, Visser LG, Kikkert M, Feltkamp MCW, Arbous SM, Staal FJT, Ottenhoff THM, van Dongen JJM, Roukens AHE, de Vries JJC, In Collaboration With Beat-Covid, In Collaboration With Lumc Covid. Zlei M, et al. Among authors: heemskerk mhm. Cells. 2022 Sep 2;11(17):2743. doi: 10.3390/cells11172743. Cells. 2022. PMID: 36078151 Free PMC article.
Human T cells recognize HLA-DP-bound peptides in two orientations.
Klobuch S, Lim JJ, van Balen P, Kester MGD, de Klerk W, de Ru AH, Pothast CR, Jedema I, Drijfhout JW, Rossjohn J, Reid HH, van Veelen PA, Falkenburg JHF, Heemskerk MHM. Klobuch S, et al. Among authors: heemskerk mhm. Proc Natl Acad Sci U S A. 2022 Dec 6;119(49):e2214331119. doi: 10.1073/pnas.2214331119. Epub 2022 Nov 29. Proc Natl Acad Sci U S A. 2022. PMID: 36442096 Free PMC article.
Immunogenicity and reactogenicity of intradermal mRNA-1273 SARS-CoV-2 vaccination: a non-inferiority, randomized-controlled trial.
Prins MLM, Roozen GVT, Pothast CR, Huisman W, van Binnendijk R, den Hartog G, Kuiper VP, Prins C, Janse JJ, Lamers OAC, Koopman JPR, Kruithof AC, Kamerling IMC, Dijkland RC, de Kroon AC, Azimi S, Feltkamp MCW, Kuijer M, Jochems SP, Heemskerk MHM, Rosendaal FR, Roestenberg M, Visser LG, Roukens AHE. Prins MLM, et al. Among authors: heemskerk mhm. NPJ Vaccines. 2024 Jan 2;9(1):1. doi: 10.1038/s41541-023-00785-w. NPJ Vaccines. 2024. PMID: 38167735 Free PMC article.
Selective graft-versus-leukemia depends on magnitude and diversity of the alloreactive T cell response.
van Bergen CA, van Luxemburg-Heijs SA, de Wreede LC, Eefting M, von dem Borne PA, van Balen P, Heemskerk MH, Mulder A, Claas FH, Navarrete MA, Honders WM, Rutten CE, Veelken H, Jedema I, Halkes CJ, Griffioen M, Falkenburg JH. van Bergen CA, et al. J Clin Invest. 2017 Feb 1;127(2):517-529. doi: 10.1172/JCI86175. Epub 2017 Jan 9. J Clin Invest. 2017. PMID: 28067665 Free PMC article.
164 results