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Initial Pharmacological Characterization of a Major Hydroxy Metabolite of PF-5190457: Inverse Agonist Activity of PF-6870961 at the Ghrelin Receptor.
Deschaine SL, Hedegaard MA, Pince CL, Farokhnia M, Moose JE, Stock IA, Adusumalli S, Akhlaghi F, Hougland JL, Sulima A, Rice KC, Koob GF, Vendruscolo LF, Holst B, Leggio L. Deschaine SL, et al. Among authors: hedegaard ma. J Pharmacol Exp Ther. 2023 Aug;386(2):117-128. doi: 10.1124/jpet.122.001393. Epub 2023 Jan 11. J Pharmacol Exp Ther. 2023. PMID: 36631279 Free PMC article.
Identification and Metabolic Profiling of a Novel Human Gut-derived LEAP2 Fragment.
Hagemann CA, Zhang C, Hansen HH, Jorsal T, Rigbolt KTG, Madsen MR, Bergmann NC, Heimbürger SMN, Falkenhahn M, Theis S, Breitschopf K, Holm S, Hedegaard MA, Christensen MB, Vilsbøll T, Holst B, Vrang N, Jelsing J, Knop FK. Hagemann CA, et al. Among authors: hedegaard ma. J Clin Endocrinol Metab. 2021 Jan 23;106(2):e966-e981. doi: 10.1210/clinem/dgaa803. J Clin Endocrinol Metab. 2021. PMID: 33135737
Falcarindiol Purified From Carrots Leads to Elevated Levels of Lipid Droplets and Upregulation of Peroxisome Proliferator-Activated Receptor-γ Gene Expression in Cellular Models.
Andersen CB, Runge Walther A, Pipó-Ollé E, Notabi MK, Juul S, Eriksen MH, Lovatt AL, Cowie R, Linnet J, Kobaek-Larsen M, El-Houri R, Andersen MØ, Hedegaard MAB, Christensen LP, Arnspang EC. Andersen CB, et al. Among authors: hedegaard mab. Front Pharmacol. 2020 Aug 28;11:565524. doi: 10.3389/fphar.2020.565524. eCollection 2020. Front Pharmacol. 2020. PMID: 32982759 Free PMC article.
Metabolic insights from a GHSR-A203E mutant mouse model.
Torz LJ, Osborne-Lawrence S, Rodriguez J, He Z, Cornejo MP, Mustafá ER, Jin C, Petersen N, Hedegaard MA, Nybo M, Damonte VM, Metzger NP, Mani BK, Williams KW, Raingo J, Perello M, Holst B, Zigman JM. Torz LJ, et al. Among authors: hedegaard ma. Mol Metab. 2020 Sep;39:101004. doi: 10.1016/j.molmet.2020.101004. Epub 2020 Apr 24. Mol Metab. 2020. PMID: 32339772 Free PMC article.
Translation Approach for Dentine Regeneration Using GSK-3 Antagonists.
Zaugg LK, Banu A, Walther AR, Chandrasekaran D, Babb RC, Salzlechner C, Hedegaard MAB, Gentleman E, Sharpe PT. Zaugg LK, et al. Among authors: hedegaard mab. J Dent Res. 2020 May;99(5):544-551. doi: 10.1177/0022034520908593. Epub 2020 Mar 10. J Dent Res. 2020. PMID: 32156176 Free PMC article.
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