Heckel AM - Search Results

1

Can Mitochondrial DNA be CRISPRized: Pro and Contra.

Loutre R, Heckel AM, Smirnova A, Entelis N, Tarassov I. Loutre R, et al. Among authors: heckel am. IUBMB Life. 2018 Dec;70(12):1233-1239. doi: 10.1002/iub.1919. Epub 2018 Sep 5. IUBMB Life. 2018. PMID: 30184317 Free article. Review.

2

Characterization of chemically modified oligonucleotides targeting a pathogenic mutation in human mitochondrial DNA.

Tonin Y, Heckel AM, Dovydenko I, Meschaninova M, Comte C, Venyaminova A, Pyshnyi D, Tarassov I, Entelis N. Tonin Y, et al. Among authors: heckel am. Biochimie. 2014 May;100:192-9. doi: 10.1016/j.biochi.2013.08.020. Epub 2013 Aug 28. Biochimie. 2014. PMID: 23994754

3

Modeling of antigenomic therapy of mitochondrial diseases by mitochondrially addressed RNA targeting a pathogenic point mutation in mitochondrial DNA.

Tonin Y, Heckel AM, Vysokikh M, Dovydenko I, Meschaninova M, Rötig A, Munnich A, Venyaminova A, Tarassov I, Entelis N. Tonin Y, et al. Among authors: heckel am. J Biol Chem. 2014 May 9;289(19):13323-34. doi: 10.1074/jbc.M113.528968. Epub 2014 Apr 1. J Biol Chem. 2014. PMID: 24692550 Free PMC article.

4

Mitochondrial targeting of recombinant RNA.

Dovydenko I, Heckel AM, Tonin Y, Gowher A, Venyaminova A, Tarassov I, Entelis N. Dovydenko I, et al. Among authors: heckel am. Methods Mol Biol. 2015;1265:209-25. doi: 10.1007/978-1-4939-2288-8_16. Methods Mol Biol. 2015. PMID: 25634278

5

Anti-replicative recombinant 5S rRNA molecules can modulate the mtDNA heteroplasmy in a glucose-dependent manner.

Loutre R, Heckel AM, Jeandard D, Tarassov I, Entelis N. Loutre R, et al. Among authors: heckel am. PLoS One. 2018 Jun 18;13(6):e0199258. doi: 10.1371/journal.pone.0199258. eCollection 2018. PLoS One. 2018. PMID: 29912984 Free PMC article.

6

Homoplasmic mitochondrial tRNA^Pro mutation causing exercise-induced muscle swelling and fatigue.

Auré K, Fayet G, Chicherin I, Rucheton B, Filaut S, Heckel AM, Eichler J, Caillon F, Péréon Y, Entelis N, Tarassov I, Lombès A. Auré K, et al. Among authors: heckel am. Neurol Genet. 2020 Jul 15;6(4):e480. doi: 10.1212/NXG.0000000000000480. eCollection 2020 Aug. Neurol Genet. 2020. PMID: 32802947 Free PMC article.

7

Lipophilic Conjugates for Carrier-Free Delivery of RNA Importable into Human Mitochondria.

Dovydenko I, Meschaninova M, Heckel AM, Tarassov I, Venyaminova A, Entelis N. Dovydenko I, et al. Among authors: heckel am. Methods Mol Biol. 2021;2277:49-67. doi: 10.1007/978-1-0716-1270-5_4. Methods Mol Biol. 2021. PMID: 34080144

8

Targeting of CRISPR-Cas12a crRNAs into human mitochondria.

Nikitchina N, Ulashchik E, Shmanai V, Heckel AM, Tarassov I, Mazunin I, Entelis N. Nikitchina N, et al. Among authors: heckel am. Biochimie. 2024 Feb;217:74-85. doi: 10.1016/j.biochi.2023.09.006. Epub 2023 Sep 9. Biochimie. 2024. PMID: 37690471

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