Hebron ML - Search Results

1

Pharmacokinetics and pharmacodynamics of a single dose Nilotinib in individuals with Parkinson's disease.

Pagan FL, Hebron ML, Wilmarth B, Torres-Yaghi Y, Lawler A, Mundel EE, Yusuf N, Starr NJ, Arellano J, Howard HH, Peyton M, Matar S, Liu X, Fowler AJ, Schwartz SL, Ahn J, Moussa C. Pagan FL, et al. Among authors: hebron ml. Pharmacol Res Perspect. 2019 Mar 12;7(2):e00470. doi: 10.1002/prp2.470. eCollection 2019 Apr. Pharmacol Res Perspect. 2019. PMID: 30906562 Free PMC article. Clinical Trial.

2

Fractalkine Mediates Communication between Pathogenic Proteins and Microglia: Implications of Anti-Inflammatory Treatments in Different Stages of Neurodegenerative Diseases.

Desforges NM, Hebron ML, Algarzae NK, Lonskaya I, Moussa CE. Desforges NM, et al. Among authors: hebron ml. Int J Alzheimers Dis. 2012;2012:345472. doi: 10.1155/2012/345472. Epub 2012 Aug 5. Int J Alzheimers Dis. 2012. PMID: 22919540 Free PMC article.

3

Diminished parkin solubility and co-localization with intraneuronal amyloid-β are associated with autophagic defects in Alzheimer's disease.

Lonskaya I, Shekoyan AR, Hebron ML, Desforges N, Algarzae NK, Moussa CE. Lonskaya I, et al. Among authors: hebron ml. J Alzheimers Dis. 2013;33(1):231-47. doi: 10.3233/JAD-2012-121141. J Alzheimers Dis. 2013. PMID: 22954671

4

Parkin prevents cortical atrophy and Aβ-induced alterations of brain metabolism: ¹³C NMR and magnetic resonance imaging studies in AD models.

Algarzae N, Hebron M, Miessau M, Moussa CE. Algarzae N, et al. Neuroscience. 2012 Dec 6;225:22-34. doi: 10.1016/j.neuroscience.2012.08.057. Epub 2012 Sep 6. Neuroscience. 2012. PMID: 22960314 Free PMC article.

5

Parkin ubiquitinates Tar-DNA binding protein-43 (TDP-43) and promotes its cytosolic accumulation via interaction with histone deacetylase 6 (HDAC6).

Hebron ML, Lonskaya I, Sharpe K, Weerasinghe PP, Algarzae NK, Shekoyan AR, Moussa CE. Hebron ML, et al. J Biol Chem. 2013 Feb 8;288(6):4103-15. doi: 10.1074/jbc.M112.419945. Epub 2012 Dec 20. J Biol Chem. 2013. PMID: 23258539 Free PMC article.

6

Decreased parkin solubility is associated with impairment of autophagy in the nigrostriatum of sporadic Parkinson's disease.

Lonskaya I, Hebron ML, Algarzae NK, Desforges N, Moussa CE. Lonskaya I, et al. Among authors: hebron ml. Neuroscience. 2013 Mar 1;232:90-105. doi: 10.1016/j.neuroscience.2012.12.018. Epub 2012 Dec 20. Neuroscience. 2013. PMID: 23262240 Free PMC article.

7

Fractalkine signaling and Tau hyper-phosphorylation are associated with autophagic alterations in lentiviral Tau and Aβ1-42 gene transfer models.

Hebron ML, Algarzae NK, Lonskaya I, Moussa C. Hebron ML, et al. Exp Neurol. 2014 Jan;251:127-38. doi: 10.1016/j.expneurol.2013.01.009. Epub 2013 Jan 16. Exp Neurol. 2014. PMID: 23333589 Free PMC article.

8

Nilotinib reverses loss of dopamine neurons and improves motor behavior via autophagic degradation of α-synuclein in Parkinson's disease models.

Hebron ML, Lonskaya I, Moussa CE. Hebron ML, et al. Hum Mol Genet. 2013 Aug 15;22(16):3315-28. doi: 10.1093/hmg/ddt192. Epub 2013 May 10. Hum Mol Genet. 2013. PMID: 23666528 Free PMC article.

9

Tyrosine kinase inhibition increases functional parkin-Beclin-1 interaction and enhances amyloid clearance and cognitive performance.

Lonskaya I, Hebron ML, Desforges NM, Franjie A, Moussa CE. Lonskaya I, et al. Among authors: hebron ml. EMBO Mol Med. 2013 Aug;5(8):1247-62. doi: 10.1002/emmm.201302771. Epub 2013 Jul 4. EMBO Mol Med. 2013. PMID: 23737459 Free PMC article.

10

Tyrosine kinase inhibition facilitates autophagic SNCA/α-synuclein clearance.

Hebron ML, Lonskaya I, Moussa CE. Hebron ML, et al. Autophagy. 2013 Aug;9(8):1249-50. doi: 10.4161/auto.25368. Epub 2013 Jun 19. Autophagy. 2013. PMID: 23787811 Free PMC article.

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