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The BRG1/SOX9 axis is critical for acinar cell-derived pancreatic tumorigenesis.
Tsuda M, Fukuda A, Roy N, Hiramatsu Y, Leonhardt L, Kakiuchi N, Hoyer K, Ogawa S, Goto N, Ikuta K, Kimura Y, Matsumoto Y, Takada Y, Yoshioka T, Maruno T, Yamaga Y, Kim GE, Akiyama H, Ogawa S, Wright CV, Saur D, Takaori K, Uemoto S, Hebrok M, Chiba T, Seno H. Tsuda M, et al. Among authors: hebrok m. J Clin Invest. 2018 Aug 1;128(8):3475-3489. doi: 10.1172/JCI94287. Epub 2018 Jul 16. J Clin Invest. 2018. PMID: 30010625 Free PMC article.
Sonic hedgehog acts at multiple stages during pancreatic tumorigenesis.
Morton JP, Mongeau ME, Klimstra DS, Morris JP, Lee YC, Kawaguchi Y, Wright CV, Hebrok M, Lewis BC. Morton JP, et al. Among authors: hebrok m. Proc Natl Acad Sci U S A. 2007 Mar 20;104(12):5103-8. doi: 10.1073/pnas.0701158104. Epub 2007 Mar 19. Proc Natl Acad Sci U S A. 2007. PMID: 17372229 Free PMC article.
Stabilization of beta-catenin induces pancreas tumor formation.
Heiser PW, Cano DA, Landsman L, Kim GE, Kench JG, Klimstra DS, Taketo MM, Biankin AV, Hebrok M. Heiser PW, et al. Among authors: hebrok m. Gastroenterology. 2008 Oct;135(4):1288-300. doi: 10.1053/j.gastro.2008.06.089. Epub 2008 Jul 9. Gastroenterology. 2008. PMID: 18725219 Free PMC article.
141 results