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Non-canonical inflammasome activation mediates the adjuvanticity of nanoparticles.
Muñoz-Wolf N, Ward RW, Hearnden CH, Sharp FA, Geoghegan J, O'Grady K, McEntee CP, Shanahan KA, Guy C, Bowie AG, Campbell M, Roces CB, Anderluzzi G, Webb C, Perrie Y, Creagh E, Lavelle EC. Muñoz-Wolf N, et al. Among authors: hearnden ch. Cell Rep Med. 2023 Jan 17;4(1):100899. doi: 10.1016/j.xcrm.2022.100899. Cell Rep Med. 2023. PMID: 36652908 Free PMC article.
Modulation of Immune Responses by Particulate Materials.
Lebre F, Hearnden CH, Lavelle EC. Lebre F, et al. Among authors: hearnden ch. Adv Mater. 2016 Jul;28(27):5525-41. doi: 10.1002/adma.201505395. Epub 2016 May 11. Adv Mater. 2016. PMID: 27167228
A Common Variant in the Adaptor Mal Regulates Interferon Gamma Signaling.
Ní Cheallaigh C, Sheedy FJ, Harris J, Muñoz-Wolf N, Lee J, West K, McDermott EP, Smyth A, Gleeson LE, Coleman M, Martinez N, Hearnden CH, Tynan GA, Carroll EC, Jones SA, Corr SC, Bernard NJ, Hughes MM, Corcoran SE, O'Sullivan M, Fallon CM, Kornfeld H, Golenbock D, Gordon SV, O'Neill LA, Lavelle EC, Keane J. Ní Cheallaigh C, et al. Among authors: hearnden ch. Immunity. 2016 Feb 16;44(2):368-79. doi: 10.1016/j.immuni.2016.01.019. Immunity. 2016. PMID: 26885859 Free PMC article.
Memory Th1 Cells Are Protective in Invasive Staphylococcus aureus Infection.
Brown AF, Murphy AG, Lalor SJ, Leech JM, O'Keeffe KM, Mac Aogáin M, O'Halloran DP, Lacey KA, Tavakol M, Hearnden CH, Fitzgerald-Hughes D, Humphreys H, Fennell JP, van Wamel WJ, Foster TJ, Geoghegan JA, Lavelle EC, Rogers TR, McLoughlin RM. Brown AF, et al. Among authors: hearnden ch. PLoS Pathog. 2015 Nov 5;11(11):e1005226. doi: 10.1371/journal.ppat.1005226. eCollection 2015. PLoS Pathog. 2015. PMID: 26539822 Free PMC article.