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Stratifin promotes renal dysfunction in ischemic and nephrotoxic AKI mouse models via enhancing RIPK3-mediated necroptosis.
Wang F, Wang JN, He XY, Suo XG, Li C, Ni WJ, Cai YT, He Y, Fang XY, Dong YH, Xing T, Yang YR, Zhang F, Zhong X, Zang HM, Liu MM, Li J, Meng XM, Jin J. Wang F, et al. Among authors: he xy, he y. Acta Pharmacol Sin. 2022 Feb;43(2):330-341. doi: 10.1038/s41401-021-00649-w. Epub 2021 Apr 8. Acta Pharmacol Sin. 2022. PMID: 33833407 Free PMC article.
Cpd-0225 attenuates renal fibrosis via inhibiting ALK5.
Xie SS, Dong ZH, He Y, Chen ZW, Yang Q, Ma WX, Li C, Chen Y, Wang JN, Yu JT, Xu CH, Ni WJ, Hou R, Suo XG, Wen JG, Jin J, Li J, Liu MM, Meng XM. Xie SS, et al. Among authors: he y. Biochem Pharmacol. 2022 Oct;204:115240. doi: 10.1016/j.bcp.2022.115240. Epub 2022 Sep 5. Biochem Pharmacol. 2022. PMID: 36070847
Compound-42 alleviates acute kidney injury by targeting RIPK3-mediated necroptosis.
He XY, Wang F, Suo XG, Gu MZ, Wang JN, Xu CH, Dong YH, He Y, Zhang Y, Ji ML, Chen Y, Zhang MM, Fan YG, Wen JG, Jin J, Wang J, Li J, Zhuang CL, Liu MM, Meng XM. He XY, et al. Among authors: he y. Br J Pharmacol. 2023 Oct;180(20):2641-2660. doi: 10.1111/bph.16152. Epub 2023 Jul 1. Br J Pharmacol. 2023. PMID: 37248964
Genetic and pharmacological inhibition of GRPR protects against acute kidney injury via attenuating renal inflammation and necroptosis.
Li C, Ma QY, Liu XQ, Li HD, Yu MJ, Xie SS, Ma WX, Chen Y, Wang JN, He RB, Bian HG, He Y, Gao L, Deng SS, Zang HM, Gong Q, Wen JG, Liu MM, Yang C, Chen HY, Li J, Lan HY, Jin J, Yao RS, Meng XM. Li C, et al. Among authors: he rb, he y. Mol Ther. 2023 Sep 6;31(9):2734-2754. doi: 10.1016/j.ymthe.2023.06.016. Epub 2023 Jul 5. Mol Ther. 2023. PMID: 37415332
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